Rebamipide

Rebamipide

SCHEMBL27858766

O=C(NC(Cc1cc(=O)[nH]c2ccccc12)C(=O)O)c1ccc(Cl)cc1.[Zn]

nearest known ligand 0.98

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UBASH3B Q8TF42 1/20 0.98
PPARG P37231 1/20 0.55
ITGB2 P05107 6/20 0.54
ICAM1 P05362 6/20 0.54
ITGAL P20701 6/20 0.54
F11 P03951 2/20 0.54
ERAP2 Q6P179 1/20 0.53
TACR1 P25103 2/20 0.52
CCKBR P32239 1/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
CA2 P00918 1/20 0.47
HDAC3 O15379 1/20 0.47
HDAC4 P56524 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC7 Q8WUI4 1/20 0.47
HDAC2 Q92769 1/20 0.47
HDAC10 Q969S8 1/20 0.47
HDAC11 Q96DB2 1/20 0.47
HDAC8 Q9BY41 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Rebamipide SCHEMBL23346201 0.99 UBASH3B (1.00) UBASH3BPPARGITGB2ICAM1ITGAL
Rebamipide SCHEMBL29560992 0.99 UBASH3B (1.00) UBASH3BPPARGITGB2ICAM1ITGAL
Rebamipide SCHEMBL221527 0.99 UBASH3B (1.00) UBASH3BPPARGITGB2ICAM1ITGAL
Rebamipide SCHEMBL21623658 0.99 UBASH3B (1.00) UBASH3BPPARGITGB2ICAM1ITGAL
Rebamipide SCHEMBL5794018 0.99 UBASH3B (1.00) UBASH3BPPARGITGB2ICAM1ITGAL
Rebamipide SCHEMBL9114879 0.98 UBASH3B (0.98) UBASH3BPPARGITGB2ICAM1ITGAL
Rebamipide SCHEMBL28341360 0.98 UBASH3B (0.98) UBASH3BPPARGITGB2ICAM1ITGAL
Rebamipide SCHEMBL28798513 0.98 UBASH3B (0.98) UBASH3BPPARGITGB2ICAM1ITGAL
Rebamipide SCHEMBL2292009 0.98 UBASH3B (0.98) UBASH3BPPARGITGB2ICAM1ITGAL
Rebamipide SCHEMBL26607915 0.98 UBASH3B (0.98) UBASH3BPPARGITGB2ICAM1ITGAL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102512420-A Officinal composite using Rebamipide officinal salt as active ingredient BEIJING FUKANGREN BIOPHARMACEUTICAL TECHNOLOGY CO LTD 2012-06-27 CN disclosed