Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL798477 | 0.85 | MCHR1 (0.35) | MCHR1 | |
| SCHEMBL29020722 | 0.82 | — | — | |
| SCHEMBL22991025 | 0.79 | MCHR1 (0.33) | MCHR1 | |
| SCHEMBL15655042 | 0.76 | HDAC1 (0.32) | — | |
| SCHEMBL31035602 | 0.75 | APP (0.31) | MCHR1 | |
| SCHEMBL18506079 | 0.75 | MCHR1 (0.41) | MCHR1 | |
| SCHEMBL23571466 | 0.73 | IRAK4 (0.33) | MCHR1 | |
| SCHEMBL12248520 | 0.73 | NOS3 (0.32) | — | |
| SCHEMBL1500198 | 0.73 | PIK3CG (0.55) | MCHR1 | |
| SCHEMBL1302277 | 0.72 | PIK3CG (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115322199-B | Compounds and their use in the treatment of schistosomiasis | 默克专利股份有限公司 | 2024-12-10 | — | — | CN | disclosed |
| CN-118684667-A | Compounds for the treatment of fasciolopsis | 默克专利股份有限公司 | 2024-09-24 | — | — | CN | disclosed |
| CN-112512636-B | Compounds for the treatment of fasciolopsis | 默克专利股份有限公司 | 2024-06-18 | — | — | CN | disclosed |
| EP-3823728-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF FASCIOLIASIS | Merck Patent GmbH (DE) | 2021-05-26 | — | — | EP | disclosed |
| WO-2020016235-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF FASCIOLIASIS | MERCK PATENT GMBH (DE) | 2020-01-23 | — | — | WO | disclosed |