SCHEMBL31035602

SCHEMBL31035602

CC(C)c1cn2cc(C(Cl)Cl)nc2cn1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.31
MCHR1 Q99705 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL798477 0.89 MCHR1 (0.35) APPMCHR1
SCHEMBL12248520 0.80 NOS3 (0.32)
SCHEMBL31035778 0.79 NOS3 (0.32)
SCHEMBL31035837 0.76
SCHEMBL22991025 0.75 MCHR1 (0.33) MCHR1
SCHEMBL21623697 0.75 MCHR1 (0.33) MCHR1
SCHEMBL12248523 0.75
SCHEMBL31035721 0.75
SCHEMBL15959463 0.75 TGFBR1 (0.35)
SCHEMBL18506079 0.71 MCHR1 (0.41) MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118434744-A Nitrogen-containing macrocyclic compound, and preparation method and medical application thereof 中国医药研究开发中心有限公司 2024-08-02 CN disclosed