Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21623741 | 0.70 | PKM (0.39) | ALDH1A1MEN1KMT2AHTTTDP1 | |
| SCHEMBL21623733 | 0.68 | PKM (0.43) | ALDH1A1MEN1KMT2AHTTTDP1 | |
| SCHEMBL21623737 | 0.67 | ADORA1 (0.38) | ALDH1A1MEN1KMT2AHTTTDP1 | |
| SCHEMBL16616570 | 0.65 | KCNQ3 (0.51) | HTTSMN1; SMN2RAB9A | |
| SCHEMBL25290699 | 0.63 | MEN1 (0.42) | MEN1KMT2ACYP1A2 | |
| SCHEMBL21051217 | 0.63 | MEN1 (0.47) | ALDH1A1MEN1KMT2AHTTTDP1 | |
| SCHEMBL25287886 | 0.62 | MEN1 (0.38) | ALDH1A1MEN1KMT2AHTTTDP1 | |
| SCHEMBL11286380 | 0.61 | TDP1 (0.44) | ALDH1A1MEN1KMT2AHTTTDP1 | |
| SCHEMBL1857458 | 0.61 | CA12 (0.42) | ALDH1A1MEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL16616466 | 0.60 | KCNQ2 (0.46) | ALDH1A1MEN1KMT2AHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020016297-A1 | THIOETHERS AS MODULATORS OF KV7.2/KV7.3 CHANNELS | Universität Greifswald (DE) | 2020-01-23 | — | — | WO | disclosed |