SCHEMBL21624232

SCHEMBL21624232

COc1ccc2c(=O)c3ccccc3sc2c1OC

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.65
HPGD P15428 3/20 0.65
NPC1 O15118 2/20 0.65
RAB9A P51151 2/20 0.65
CYP1A2 P05177 1/20 0.65
CYP3A4 P08684 1/20 0.65
CYP2C9 P11712 1/20 0.65
CYP2C19 P33261 1/20 0.65
ALDH1A1 P00352 4/20 0.50
L3MBTL1 Q9Y468 3/20 0.50
KDM4E B2RXH2 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
MAOA P21397 2/20 0.50
HCRTR1 O43613 2/20 0.44
LMNA P02545 1/20 0.44
POLB P06746 1/20 0.44
MEN1 O00255 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31676781 1.00 MAPT (0.65) MAPTHPGDNPC1RAB9ACYP1A2
SCHEMBL5030886 0.83 MAPT (0.54) MAPTHPGDNPC1RAB9ACYP1A2
SCHEMBL30998134 0.83 MAPT (0.54) MAPTHPGDNPC1RAB9ACYP1A2
SCHEMBL21624267 0.82 NPC1 (0.58) MAPTHPGDNPC1RAB9ACYP1A2
SCHEMBL30018369 0.82 NPC1 (0.58) MAPTHPGDNPC1RAB9ACYP1A2
SCHEMBL21624229 0.82 MAPT (0.50) MAPTHPGDNPC1RAB9ACYP1A2
SCHEMBL10498795 0.79 MAPT (0.45) MAPTHPGDNPC1RAB9ACYP1A2
SCHEMBL31157858 0.79 NPC1 (1.00) MAPTHPGDNPC1RAB9ACYP1A2
SCHEMBL4306920 0.79 NPC1 (1.00) MAPTHPGDNPC1RAB9ACYP1A2
SCHEMBL30173371 0.78 MAPT (0.44) MAPTHPGDNPC1RAB9ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230082557-A1 Modified Thioxanthone Photoinitiators LINTFIELD LIMITED (GB) 2023-03-16 US claimed
EP-4090656-A1 MODIFIED THIOXANTHONE PHOTOINITIATORS Lintfield Limited (GB) 2022-11-23 EP claimed
CN-115279744-A Modified thioxanthone photoinitiators 林特弗德有限公司 2022-11-01 CN claimed
US-20210277017-A1 Thioxanthone Derivatives, Composition Comprising the Same and Pattern Forming Method Comprising Said Composition LINTFIELD LIMITED (GB) 2021-09-09 US claimed
WO-2021144582-A1 MODIFIED THIOXANTHONE PHOTOINITIATORS LINTFIELD LIMITED (GB) 2021-07-22 WO claimed
CN-112969965-A Thioxanthone derivative, composition comprising the same, and pattern forming method comprising the composition 林特弗德有限公司 2021-06-15 CN claimed
EP-3824349-A1 THIOXANTHONE DERIVATIVES, COMPOSITION COMPRISING THE SAME AND PATTERN FORMING METHOD COMPRISING SAID COMPOSITION Lintfield Limited (GB) 2021-05-26 EP claimed
WO-2020016389-A1 THIOXANTHONE DERIVATIVES, COMPOSITION COMPRISING THE SAME AND PATTERN FORMING METHOD COMPRISING SAID COMPOSITION LINTFIELD LIMITED (GB) 2020-01-23 WO claimed
US-12398152-B2 Thioxanthone derivatives, composition comprising the same and pattern forming method comprising said composition LINTFIELD LIMITED (GB) 2025-08-26 US disclosed
US-20210277017-A1 Thioxanthone Derivatives, Composition Comprising the Same and Pattern Forming Method Comprising Said Composition LINTFIELD LIMITED (GB) 2021-09-09 US disclosed
US-20210277017-A1 Thioxanthone Derivatives, Composition Comprising the Same and Pattern Forming Method Comprising Said Composition LINTFIELD LIMITED (GB) 2021-09-09 US disclosed
CN-112969965-A Thioxanthone derivative, composition comprising the same, and pattern forming method comprising the composition 林特弗德有限公司 2021-06-15 CN disclosed
EP-3824349-A1 THIOXANTHONE DERIVATIVES, COMPOSITION COMPRISING THE SAME AND PATTERN FORMING METHOD COMPRISING SAID COMPOSITION Lintfield Limited (GB) 2021-05-26 EP disclosed
WO-2020016389-A1 THIOXANTHONE DERIVATIVES, COMPOSITION COMPRISING THE SAME AND PATTERN FORMING METHOD COMPRISING SAID COMPOSITION LINTFIELD LIMITED (GB) 2020-01-23 WO disclosed
WO-2020016389-A1 THIOXANTHONE DERIVATIVES, COMPOSITION COMPRISING THE SAME AND PATTERN FORMING METHOD COMPRISING SAID COMPOSITION LINTFIELD LIMITED (GB) 2020-01-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230082557-A1 Modified Thioxanthone Photoinitiators TPMT, PPOX, TST MAPT 352/4885HPGD 544/4885NPC1 3344/4885
US-12398152-B2 Thioxanthone derivatives, composition comprising the same and pattern forming method comprising said composition TPMT, TST, PPOX MAPT 410/4885HPGD 829/4885NPC1 2592/4885
US-20210277017-A1 Thioxanthone Derivatives, Composition Comprising the Same and Pattern Forming Method Comprising Said Composition TPMT, TST, PPOX MAPT 410/4885HPGD 829/4885NPC1 2592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.