Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | RGS12 | O14924 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15085672 | 1.00 | TNF (0.43) | TNFBLMKMT2AMEN1KDM4E | |
| SCHEMBL30611533 | 0.89 | ALDH1A1 (0.47) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL23387521 | 0.89 | ALDH1A1 (0.47) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL15105505 | 0.89 | ALDH1A1 (0.47) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL27984915 | 0.86 | GRIK1 (0.39) | GRIK1GRIK2 | |
| SCHEMBL31070923 | 0.86 | TNF (0.43) | TNFBLMKMT2AMEN1KDM4E | |
| SCHEMBL15085696 | 0.86 | TNF (0.43) | TNFBLMKMT2AMEN1KDM4E | |
| SCHEMBL15105507 | 0.81 | CYP2D6 (0.39) | TNFKMT2AMEN1KDM4ELMNA | |
| SCHEMBL5287555 | 0.80 | KDM4E (0.53) | TNFBLMKMT2AMEN1KDM4E | |
| SCHEMBL13957680 | 0.79 | IDO1 (0.53) | BLMKMT2AMEN1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109195601-A | Pharmaceutical composition for treating cancer | 迪美公司 | 2019-01-11 | — | — | CN | claimed |
| EP-3823626-A1 | COMPOSITIONS AND METHODS FOR TREATING AUTISM | Yamo Pharmaceuticals LLC (US) | 2021-05-26 | — | — | EP | disclosed |
| EP-3823593-A1 | COMPOSITIONS AND METHODS FOR TREATING AUTISM | Yamo Pharmaceuticals LLC (US) | 2021-05-26 | — | — | EP | disclosed |
| WO-2020018291-A1 | COMPOSITIONS AND METHODS FOR TREATING AUTISM | YAMO PHARMACEUTICALS LLC (US) | 2020-01-23 | — | — | WO | disclosed |
| WO-2020018292-A1 | COMPOSITIONS AND METHODS FOR TREATING AUTISM | YAMO PHARMACEUTICALS LLC (US) | 2020-01-23 | — | — | WO | disclosed |
| CN-107714684-A | Pharmaceutical composition and its application comprising α methyl DL tyrosine | 迪美公司 | 2018-02-23 | — | — | CN | disclosed |
| CN-104220057-B | Pharmaceutical compositions and methods | 迪美公司 | 2017-11-03 | — | — | CN | disclosed |