Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | TPH1 | P17752 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31070923 | 1.00 | TNF (0.43) | TNFKDM1AMAOBLDHATPH1 | |
| SCHEMBL30036400 | 0.87 | ALDH1A1 (0.46) | KDM1AMAOBKDM4EMEN1KMT2A | |
| SCHEMBL15105461 | 0.87 | ALDH1A1 (0.46) | KDM1AMAOBKDM4EMEN1KMT2A | |
| SCHEMBL23387526 | 0.87 | ALDH1A1 (0.46) | KDM1AMAOBKDM4EMEN1KMT2A | |
| SCHEMBL2675348 | 0.87 | KDM4E (0.48) | LDHATPH1KDM4EMAPTMEN1 | |
| SCHEMBL2675352 | 0.87 | KDM4E (0.48) | LDHATPH1KDM4EMAPTMEN1 | |
| SCHEMBL15085672 | 0.86 | TNF (0.43) | TNFLDHATPH1KDM4EMAPT | |
| SCHEMBL21625554 | 0.86 | TNF (0.43) | TNFLDHATPH1KDM4EMAPT | |
| SCHEMBL28719998 | 0.83 | NOS3 (0.42) | TPH1KDM4EMAPTMEN1LMNA | |
| SCHEMBL15105463 | 0.81 | KDM4E (0.43) | KDM1AMAOBLDHAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 231 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11931329-B2 | Compositions and methods for treating anxiety-related disorders | YAMO PHARMACEUTICALS LLC (US) | 2024-03-19 | — | — | US | claimed |
| US-20240024268-A1 | Methods for Dopamine Modulation in Human Neurologic Diseases | SACKNER BERNSTEIN JONATHAN (US) | 2024-01-25 | — | — | US | claimed |
| US-20240016815-A1 | COMPOSITIONS AND METHODS FOR MODULATING CANCER IN NON-HUMAN MAMMALS | HOFFMAN TECHNOLOGIES LLC | 2024-01-18 | — | — | US | claimed |
| US-11806326-B2 | Methods for dopamine modulation in human neurologic diseases | SACKNER BERNSTEIN JONATHAN (US) | 2023-11-07 | — | — | US | claimed |
| US-11786496-B2 | Composition and methods for treating intestinal hyperpermeability | YAMO PHARMACEUTICALS LLC (US) | 2023-10-17 | — | — | US | claimed |
| US-20230141609-A1 | Methods of Treating Amyotrophic Lateral Sclerosis and Symptoms | YAMO PHARMACEUTICALS LLC (US) | 2023-05-11 | — | — | US | claimed |
| US-20230040681-A1 | COMPOSITIONS AND METHODS FOR TREATING ANXIETY-RELATED DISORDERS | YAMO PHARMACEUTICALS LLC (US) | 2023-02-09 | — | — | US | claimed |
| US-11534420-B2 | Compositions and methods for treating cancer | TYME, INC. (US) | 2022-12-27 | — | — | US | claimed |
| CN-115515575-A | Tyrosine derivatives for the modulation of cancer | 迪美公司 | 2022-12-23 | — | — | CN | claimed |
| CN-114901272-A | Sustained release preparation | 霍夫曼技术有限责任公司 | 2022-08-12 | — | — | CN | claimed |
| WO-2015061288-A1 | TYROSINE DERIVATIVES AND COMPOSITIONS COMPRISING THEM | TYME, INC. (US) | 2015-04-30 | — | — | WO | claimed |
| WO-2015061256-A1 | HIGH-SPEED CENTRIFUGAL MIXING DEVICES AND METHODS OF USE | TYME, INC. (US) | 2015-04-30 | — | — | WO | claimed |
| US-20150112116-A1 | TYROSINE DERIVATIVES AND COMPOSITIONS COMPRISING THEM | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2015-04-23 | — | — | US | claimed |
| US-20150111878-A1 | COMPOSITIONS AND METHODS FOR TREATING INTESTINAL HYPERPERMEABILITY | HOFFMAN STEVEN (US) | 2015-04-23 | — | — | US | claimed |
| US-20150110735-A1 | HIGH-SPEED CENTRIFUGAL MIXING DEVICES AND METHODS OF USE | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2015-04-23 | — | — | US | claimed |
| US-20150111937-A1 | Compositions and Methods for Treating Intestinal Hyperpermeability | YAMO PHARMACEUTICALS LLC | 2015-04-23 | — | — | US | claimed |
| EP-2804599-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS | Tyme, Inc. (US) | 2014-11-26 | — | — | EP | claimed |
| WO-2013109610-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS | HOFFMAN STEVEN (US) | 2013-07-25 | — | — | WO | claimed |
| US-20130184214-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2013-07-18 | — | — | US | claimed |
| US-8481498-B1 | Pharmaceutical compositions and methods | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2013-07-09 | — | — | US | claimed |