Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.46 |
| ▸ | RELA | Q04206 | 3/20 | 0.46 |
| ▸ | MPO | P05164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | BCR | P11274 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21626767 | 0.89 | CYP1A2 (0.53) | GAARAB9ANPC1MAPTMEN1 | |
| SCHEMBL21626750 | 0.88 | RAB9A (0.51) | GAARAB9ANPC1MAPTMEN1 | |
| SCHEMBL16566653 | 0.84 | CYP1A2 (0.57) | GAARAB9ANPC1MAPTMEN1 | |
| SCHEMBL19764161 | 0.83 | NOX1 (0.68) | GAARAB9ANPC1MAPTMEN1 | |
| SCHEMBL30389995 | 0.82 | NOX1 (0.67) | GAARAB9ANPC1MAPTMEN1 | |
| SCHEMBL21626686 | 0.82 | RAB9A (0.62) | GAARAB9ANPC1MAPTMEN1 | |
| SCHEMBL20625514 | 0.82 | MAPT (0.62) | GAARAB9ANPC1MAPTMEN1 | |
| SCHEMBL20625511 | 0.82 | KCNH2 (0.58) | GAARAB9ANPC1MAPTMEN1 | |
| SCHEMBL21626751 | 0.80 | RAB9A (0.56) | GAARAB9ANPC1MAPTMEN1 | |
| SCHEMBL13875562 | 0.79 | GAA (0.69) | GAARAB9ANPC1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200024224-A1 | ANTIFUNGAL COMPOUNDS AND METHODS OF FORMING THE SAME | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2020-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200024224-A1 | ANTIFUNGAL COMPOUNDS AND METHODS OF FORMING THE SAME | DPM1, ERG28, SUCLG1 | GAA 202/4885RAB9A 3696/4885NPC1 544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.