SCHEMBL216268

SCHEMBL216268

C=Cc1cccc(C(F)(F)F)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 1/20 0.55
FBP1 P09467 1/20 0.51
TSHR P16473 1/20 0.48
MAPK1 P28482 1/20 0.48
TP53 P04637 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
MEN1 O00255 2/20 0.45
MAPT P10636 2/20 0.45
KMT2A Q03164 2/20 0.45
CISD1 Q9NZ45 2/20 0.45
TTR P02766 1/20 0.45
PIM1 P11309 1/20 0.45
PIM2 Q9P1W9 1/20 0.45
P4HB P07237 1/20 0.45
LMNA P02545 1/20 0.45
HSP90AA1 P07900 1/20 0.45
PKM P14618 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29446987 1.00 NFE2L2 (0.55) NFE2L2FBP1TSHRMAPK1TP53
Methane SCHEMBL11607237 0.98 NFE2L2 (0.53) NFE2L2FBP1TSHRMAPK1TP53
Cyanide SCHEMBL27859717 0.94 NFE2L2 (0.50) NFE2L2FBP1TSHRMAPK1TP53
SCHEMBL22719491 0.84 L3MBTL1 (0.49) NFE2L2FBP1MAPTNPSR1MAOB
SCHEMBL29504916 0.84 L3MBTL1 (0.49) NFE2L2FBP1MAPTNPSR1MAOB
SCHEMBL11133923 0.83 MAOB (0.56) NFE2L2TDP1MAPTRAB9AMAOB
SCHEMBL2875032 0.83 TP53 (0.50) NFE2L2FBP1TSHRTP53TDP1
SCHEMBL3237563 0.82 NFE2L2 (0.58) NFE2L2FBP1TSHRMAPK1MEN1
SCHEMBL27897009 0.81 NFE2L2 (0.43) NFE2L2FBP1TP53TDP1
SCHEMBL4598751 0.80 TP53 (0.42) NFE2L2FBP1TSHRMAPK1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12372503-B2 Multifunctional magnetic tags for mud logging SAUDI ARABIAN OIL COMPANY (SA) 2025-07-29 US claimed
EP-4540297-A1 PHOTOCURABLE COMPOSITIONS AND METHODS FOR DELIVERING RADIATION TO A SUBJECT Theragenics Corporation (US) 2025-04-23 EP claimed
CN-119182083-B High-strength MPP cable protection tube 浙江飞龙管业集团有限公司 2025-03-11 CN claimed
CN-119264917-A Environment-friendly fluorine-containing surfactant, preparation method and application 浙江巨化技术中心有限公司 2025-01-07 CN claimed
CN-119182083-A High-strength MPP cable protection tube 浙江飞龙管业集团有限公司 2024-12-24 CN claimed
CN-118336112-A Thermally responsive safety additive, composition for electrolyte, preparation method of electrolyte and battery 国网湖南省电力有限公司 2024-07-12 CN claimed
US-20240207456-A1 PHOTOCURABLE COMPOSITIONS AND METHODS FOR DELIVERING RADIATION TO A SUBJECT AQUARIAN CREDIT FUNDING LLC 2024-06-27 US claimed
CN-117926288-A Method for electrochemically synthesizing 1, 4-diphenyl butane derivative under mild condition 湘潭大学 2024-04-26 CN claimed
CN-117855600-A Gel polymer electrolyte and application thereof 广州天赐高新材料股份有限公司 2024-04-09 CN claimed
CN-117430544-A Method for preparing isoindoline compound by taking alpha-amino acetal as substrate 南京工业大学 2024-01-23 CN claimed
US-20030064608-A1 Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition SABNIS RAM W (US) 2003-04-03 US claimed
US-20030054117-A1 Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition BREWER SCIENCE, INC. 2003-03-20 US claimed
WO-2002062593-A1 POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION BREWER SCIENCE, INC. (US) 2002-08-15 WO claimed
US-6376548-B1 FUNGICIDES; HERBICIDES; INSECTICIDES ROHM AND HAAS COMPANY 2002-04-23 US claimed
US-6319424-B1 WATER SOLUBLE COPOLYMER OF ACRYLAMIDE, ACRYLONITRILE, OR ACRYLOYL CHLORIDE AND STYRENE, 3-(TRIFLUOROMETHYL)STYRENE, OR NONYLPHENYL METHACRYLATE; SURFACTANT, LIQUID CRYSTAL AND WATER KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2001-11-20 US claimed
EP-0735142-B1 Process for producing (R)-styrene oxides SUMIKA FINE CHEMICALS CO LTD (JP) 2001-10-24 EP claimed
US-6265499-B1 POLYMERIZING MIXTURE MENICON CO., LTD. (JP) 2001-07-24 US claimed
EP-0433749-A2 Pyrazolin-5-on-derivatives BAYER AG (DE) 1991-06-26 EP claimed
EP-0412058-A1 1-acyl-2-pyrrolidinones as enhancers of learning and memory and pharmaceutical compositions containing same Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) 1991-02-06 EP claimed
US-4420225-A Lens of a homo- or copolymer of a fluorine containing styrene polymer BAYER AKTIENGESELLSCHAFT (DE) 1983-12-13 US claimed