SCHEMBL2162691

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2163727	0.86	SMPD3 (0.43)	PDE10AMAPK8HTR3EHTR3BHTR3A
	SCHEMBL17274183	0.86	SMPD3 (0.41)	ALDH1A1POLBPDE10ANPSR1PTPN2
	SCHEMBL23048328	0.86	SMPD3 (0.41)	ALDH1A1POLBPDE10ANPSR1PTPN2
	SCHEMBL12324150	0.86	POLB (0.40)	ALDH1A1POLBPDE10ANPSR1PTPN2
	SCHEMBL25801350	0.86	SMPD3 (0.41)	ALDH1A1POLBPDE10ANPSR1PTPN2
	SCHEMBL18053572	0.83	POLB (0.43)	ALDH1A1POLBPDE10ANPSR1PTPN2
	SCHEMBL20128584	0.83	POLB (0.38)	ALDH1A1POLBPDE10ANPSR1PTPN2
	SCHEMBL17274204	0.81	HTR3E (0.36)	ALDH1A1POLBPDE10ANPSR1HTR3E
	SCHEMBL25801001	0.81	HTR3E (0.36)	ALDH1A1POLBPDE10ANPSR1HTR3E
	SCHEMBL23964777	0.80	POLB (0.39)	POLBPTPN2PTPN1HTR3EHTR3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.