Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | FYN | P06241 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7970746 | 0.87 | LCK (0.69) | LCKFYNKDM4ECYP3A4HSD17B10 | |
| SCHEMBL31412873 | 0.84 | LCK (0.76) | LCKFYNKDM4ELMNACYP3A4 | |
| SCHEMBL2157945 | 0.84 | LCK (0.76) | LCKFYNKDM4ELMNACYP3A4 | |
| SCHEMBL661672 | 0.84 | HTT (0.56) | LCKFYNKDM4ELMNACYP3A4 | |
| SCHEMBL24379203 | 0.82 | LCK (0.53) | LCKFYNKDM4ELMNACYP3A4 | |
| SCHEMBL30210988 | 0.82 | LCK (0.53) | LCKFYNKDM4ELMNACYP3A4 | |
| SCHEMBL1300913 | 0.77 | HSD17B2 (0.55) | LCKFYNLMNACYP3A4HPGD | |
| SCHEMBL12072023 | 0.76 | HTT (0.61) | LCKFYNKDM4ELMNACYP3A4 | |
| SCHEMBL19361333 | 0.74 | ALOX5 (0.48) | LCKFYNERN1ALOX5PTGS2 | |
| SCHEMBL17169780 | 0.74 | ALOX5 (0.48) | LCKFYNMAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2146719-B1 | PROCESS FOR MAKING GALANTAMINE | SCINOPHARM TAIWAN LTD (TW) | 2013-08-14 | — | — | EP | disclosed |
| US-7985879-B2 | reacting a 5-hydroxy-4-methoxy benzoic acid derivative with N-methyl-N-(2-[4-hydroxyphenyl]ethyl)amine, to form N-methyl-N-(2-[4-hydroxyphenyl]ethyl)-5-hydroxy-4-methoxy benzene carboxamide, which is useful as an intermediate in the synthesis of lycoremine | SCINOPHARM TAIWAN LTD. (TW) | 2011-07-26 | — | — | US | disclosed |
| CN-101674835-A | Process for preparing galanthamine | SCINOPHARM TAIWAN LTD | 2010-03-17 | — | — | CN | disclosed |
| EP-2146719-A1 | PROCESS FOR MAKING GALANTAMINE | ScinoPharm Taiwan, Ltd. (TW) | 2010-01-27 | — | — | EP | disclosed |
| WO-2008127560-A1 | PROCESS FOR MAKING GALANTAMINE | SCINOPHARM TAIWAN LTD. (TW) | 2008-10-23 | — | — | WO | disclosed |
| US-20080255347-A1 | Process for making galantamine | SCINOPHARM TAIWAN LTD. | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255347-A1 | Process for making galantamine | GALR2, GALE, GALR1 | LCK 4656/4885FYN 2731/4885KDM4E 482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.