Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | DAO | P14920 | 1/20 | 0.56 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL3266320 | 0.85 | TSHR (0.64) | TSHRDAONAPRTALDH1A1L3MBTL1 | |
| Benzoic Acid SCHEMBL2921097 | 0.82 | TSHR (0.58) | TSHRDAONAPRTALDH1A1CES1 | |
| Benzoic Acid SCHEMBL27835214 | 0.80 | TSHR (0.78) | TSHRDAONAPRTALDH1A1L3MBTL1 | |
| Benzoic Acid SCHEMBL27410268 | 0.80 | TSHR (0.78) | TSHRDAONAPRTALDH1A1L3MBTL1 | |
| Benzoic Acid SCHEMBL606680 | 0.80 | TSHR (0.78) | TSHRDAONAPRTALDH1A1L3MBTL1 | |
| Benzoic Acid SCHEMBL207614 | 0.80 | TSHR (0.78) | TSHRDAONAPRTALDH1A1L3MBTL1 | |
| Benzoic Acid SCHEMBL9347407 | 0.80 | TSHR (0.78) | TSHRDAONAPRTALDH1A1L3MBTL1 | |
| Benzoic Acid SCHEMBL2779805 | 0.80 | TSHR (0.78) | TSHRDAONAPRTALDH1A1L3MBTL1 | |
| Benzoic Acid SCHEMBL1254290 | 0.80 | TSHR (0.78) | TSHRDAONAPRTALDH1A1L3MBTL1 | |
| Benzoic Acid SCHEMBL226025 | 0.80 | TSHR (0.78) | TSHRDAONAPRTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12312377-B2 | Biconjugatable labels and methods of use | Quantum-Si Incorporated (US) | 2025-05-27 | — | — | US | disclosed |
| US-20200031861-A1 | BICONJUGATABLE LABELS AND METHODS OF USE | Quantum-Si Incorporated (US) | 2020-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200031861-A1 | BICONJUGATABLE LABELS AND METHODS OF USE | CLTB, HLCS, CD44 | TSHR 3475/4885DAO 982/4885NAPRT 2642/4885 |
| US-12312377-B2 | Biconjugatable labels and methods of use | CLTB, HLCS, CD44 | TSHR 3475/4885DAO 982/4885NAPRT 2642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.