Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.55 |
| ▸ | KHK | P50053 | 1/20 | 0.54 |
| ▸ | DPP4 | P27487 | 4/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.48 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.47 |
| ▸ | BPTF | Q12830 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL314421 | 1.00 | NOTUM (0.55) | NOTUMKHKDPP4NAMPTMBTD1 | |
| SCHEMBL8386956 | 1.00 | NOTUM (0.55) | NOTUMKHKDPP4NAMPTMBTD1 | |
| Hydrochloric Acid SCHEMBL30775632 | 0.98 | NOTUM (0.53) | NOTUMKHKDPP4NAMPTMBTD1 | |
| Hydrochloric Acid SCHEMBL30775623 | 0.98 | NOTUM (0.53) | NOTUMKHKDPP4NAMPTMBTD1 | |
| SCHEMBL21460347 | 0.89 | NAMPT (0.50) | NOTUMKHKDPP4NAMPTHRH4 | |
| SCHEMBL21460344 | 0.89 | NAMPT (0.50) | NOTUMKHKDPP4NAMPTHRH4 | |
| SCHEMBL12073215 | 0.88 | NOTUM (0.47) | NOTUMKHKDPP4NAMPTMBTD1 | |
| SCHEMBL2657503 | 0.88 | NOTUM (0.47) | NOTUMKHKDPP4NAMPTMBTD1 | |
| SCHEMBL931643 | 0.87 | MBTD1 (0.57) | NOTUMDPP4MBTD1L3MBTL3L3MBTL1 | |
| Hydrochloric Acid SCHEMBL4009258 | 0.86 | NOTUM (0.46) | NOTUMKHKDPP4NAMPTMBTD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101511190-A | Pressure sensor fault detection | JANSSEN PHARMACEUTICA NV (BE) | 2009-08-19 | — | — | CN | claimed |
| CN-117177744-A | CDK2 inhibitors and methods of use thereof | 塞迪拉治疗股份有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-109311854-B | Benzazepine dicarboxamide compounds having secondary amide functionality | 豪夫迈·罗氏有限公司 | 2021-08-10 | — | — | CN | disclosed |
| US-10544102-B2 | Benzazepine dicarboxamide compounds with secondary amide function | HOFFMANN-LA ROCHE INC. (US) | 2020-01-28 | — | — | US | disclosed |
| CN-109311854-A | Benzazepine diformamide compound with secondary amide functional group | 豪夫迈·罗氏有限公司 | 2019-02-05 | — | — | CN | disclosed |
| CN-101511190-A | Pressure sensor fault detection | JANSSEN PHARMACEUTICA NV (BE) | 2009-08-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544102-B2 | Benzazepine dicarboxamide compounds with secondary amide function | TLR1, TLR5, TLR4 | NOTUM 1701/4885KHK 3044/4885DPP4 541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.