Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.41 |
| ▸ | ATP4A | P20648 | 1/20 | 0.40 |
| ▸ | ATP4B | P51164 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 2/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.40 |
| ▸ | TDO2 | P48775 | 4/20 | 0.39 |
| ▸ | FLT3 | P36888 | 2/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.38 |
| ▸ | CCNK | O75909 | 2/20 | 0.38 |
| ▸ | CDK7 | P50613 | 2/20 | 0.38 |
| ▸ | CDK9 | P50750 | 2/20 | 0.38 |
| ▸ | CCNH | P51946 | 2/20 | 0.38 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.38 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30554763 | 1.00 | MAP3K14 (0.52) | MAP3K14MEN1KMT2ARPS6KA5ATP4A | |
| SCHEMBL30554773 | 0.89 | RPS6KA5 (0.53) | MAP3K14MEN1KMT2ARPS6KA5ATP4A | |
| SCHEMBL20680088 | 0.89 | RPS6KA5 (0.53) | MAP3K14MEN1KMT2ARPS6KA5ATP4A | |
| SCHEMBL21629023 | 0.87 | MEN1 (0.45) | MAP3K14MEN1KMT2ARPS6KA5ATP4A | |
| SCHEMBL30554780 | 0.87 | MEN1 (0.45) | MAP3K14MEN1KMT2ARPS6KA5ATP4A | |
| SCHEMBL25600700 | 0.86 | CCNK (0.48) | MAP3K14RPS6KA5CCNT1CCNKCDK7 | |
| SCHEMBL19532565 | 0.85 | DYRK1A (0.51) | MAP3K14MEN1KMT2ACLK1TDO2 | |
| SCHEMBL29488129 | 0.84 | MAP3K14 (0.65) | MAP3K14MEN1KMT2AATP4AATP4B | |
| SCHEMBL21629046 | 0.84 | CCNK (0.44) | MEN1KMT2ACCNT1CCNKCDK7 | |
| SCHEMBL30554768 | 0.84 | CCNK (0.44) | MEN1KMT2ACCNT1CCNKCDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260092051-A1 | PYRIMIDINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR PREVENTING OR TREATING CANCERS INCLUDING THE SAME | HANMI PHARMACEUTICAL CO LTD (KR) | 2026-04-02 | — | — | US | disclosed |
| US-12325698-B2 | Pyrimidine compounds and pharmaceutical compositions for preventing or treating cancers including the same | HANMI PHARM. CO., LTD. (KR) | 2025-06-10 | — | — | US | disclosed |
| CN-112469715-B | Pyrimidine compound and pharmaceutical composition for preventing or treating cancer comprising the same | 韩美药品株式会社 | 2024-06-11 | — | — | CN | disclosed |
| CN-116693506-A | Pyrimidine compound and pharmaceutical composition for preventing or treating cancer comprising the same | 韩美药品株式会社 | 2023-09-05 | — | — | CN | disclosed |
| US-20230002358-A1 | PYRIMIDINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR PREVENTING OR TREATING CANCERS INCLUDING THE SAME | HANMI PHARM. CO., LTD. (KR) | 2023-01-05 | — | — | US | disclosed |
| US-11292786-B2 | Pyrimidine compounds and pharmaceutical compositions for preventing or treating cancers including the same | HANMI PHARM. CO., LTD. (KR) | 2022-04-05 | — | — | US | disclosed |
| EP-3810601-A1 | PYRIMIDINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR PREVENTING OR TREATING CANCERS INCLUDING THE SAME | Hanmi Pharm. Co., Ltd. (KR) | 2021-04-28 | — | — | EP | disclosed |
| CN-112469715-A | Pyrimidine compound and pharmaceutical composition for preventing or treating cancer comprising the same | 韩美药品株式会社 | 2021-03-09 | — | — | CN | disclosed |
| US-10870639-B2 | Pyrimidine compounds and pharmaceutical compositions for preventing or treating cancers including the same | HANMI PHARM. CO.. LTD. (KR) | 2020-12-22 | — | — | US | disclosed |
| US-20200255410-A1 | PYRIMIDINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR PREVENTING OR TREATING CANCERS INCLUDING THE SAME | HANMI PHARM. CO., LTD. (KR) | 2020-08-13 | — | — | US | disclosed |
| US-20200031806-A1 | PYRIMIDINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR PREVENTING OR TREATING CANCERS INCLUDING THE SAME | HANMI PHARM. CO., LTD. (KR) | 2020-01-30 | — | — | US | disclosed |
| WO-2020022600-A1 | PYRIMIDINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR PREVENTING OR TREATING CANCERS INCLUDING THE SAME | HANMI PHARM. CO., LTD. (KR) | 2020-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002358-A1 | PYRIMIDINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR PREVENTING OR TREATING CANCERS INCLUDING THE SAME | DPYD, TYMS, TYMP | MAP3K14 2292/4885MEN1 1082/4885KMT2A 2212/4885 |
| US-12325698-B2 | Pyrimidine compounds and pharmaceutical compositions for preventing or treating cancers including the same | DPYD, TYMS, TYMP | MAP3K14 2292/4885MEN1 1082/4885KMT2A 2212/4885 |
| US-11292786-B2 | Pyrimidine compounds and pharmaceutical compositions for preventing or treating cancers including the same | DPYD, TYMS, TYMP | MAP3K14 2292/4885MEN1 1082/4885KMT2A 2212/4885 |
| US-20200031806-A1 | PYRIMIDINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR PREVENTING OR TREATING CANCERS INCLUDING THE SAME | DPYD, TYMS, TYMP | MAP3K14 2292/4885MEN1 1082/4885KMT2A 2212/4885 |
| US-20200255410-A1 | PYRIMIDINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR PREVENTING OR TREATING CANCERS INCLUDING THE SAME | DPYD, TYMS, TYMP | MAP3K14 2292/4885MEN1 1082/4885KMT2A 2212/4885 |
| US-20260092051-A1 | PYRIMIDINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR PREVENTING OR TREATING CANCERS INCLUDING THE SAME | FLT3, FLT1, ADK | MAP3K14 345/4885MEN1 4007/4885KMT2A 1769/4885 |
| US-10870639-B2 | Pyrimidine compounds and pharmaceutical compositions for preventing or treating cancers including the same | DPYD, TYMS, TYMP | MAP3K14 2292/4885MEN1 1082/4885KMT2A 2212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.