Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PTPRB | P23467 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.39 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7716798 | 0.86 | ESR1 (0.46) | ESR1ESR2ALDH1A1THRBCYP2C9 | |
| SCHEMBL15495960 | 0.86 | ESR1 (0.46) | ESR1ESR2ALDH1A1THRBCYP2C9 | |
| SCHEMBL13572956 | 0.83 | FPR2 (0.49) | ESR1ESR2ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL7597924 | 0.83 | FPR2 (0.49) | ESR1ESR2ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL6575200 | 0.83 | FPR2 (0.49) | ESR1ESR2ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL7454243 | 0.82 | NPC1 (0.50) | ALDH1A1THRBHSD17B10TAS1R3TAS1R1 | |
| SCHEMBL14590363 | 0.81 | ATM (0.50) | ESR1ESR2ALDH1A1THRBCYP2C9 | |
| SCHEMBL6575139 | 0.81 | ATM (0.50) | ESR1ESR2ALDH1A1THRBCYP2C9 | |
| SCHEMBL15314148 | 0.81 | ESR1 (0.65) | ESR1ESR2MIFKMT2A | |
| SCHEMBL5546946 | 0.81 | ESR1 (0.65) | ESR1ESR2MIFKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11370742-B2 | Process and intermediates for the preparation of bilastine | FAES FARMA, S.A. | 2022-06-28 | — | — | US | disclosed |
| EP-3826997-B1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF BILASTINE | FAES FARMA SA (ES) | 2021-11-10 | — | — | EP | disclosed |
| US-20210300856-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF BILASTINE | FAES FARMA, S.A. (ES) | 2021-09-30 | — | — | US | disclosed |
| EP-3826997-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF BILASTINE | FAES FARMA, S.A. (ES) | 2021-06-02 | — | — | EP | disclosed |
| CN-112469709-A | Preparation method of bilastine and intermediate thereof | 费斯制药股份有限公司 | 2021-03-09 | — | — | CN | disclosed |
| WO-2020020873-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF BILASTINE | FAES FARMA, S.A. (ES) | 2020-01-30 | — | — | WO | disclosed |
| EP-3599235-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF BILASTINE | FAES FARMA, S.A. (ES) | 2020-01-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210300856-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF BILASTINE | CYP1B1, CYP2E1, CYP1A1 | ESR1 1214/4885ESR2 1839/4885ALDH1A1 1046/4885 |
| US-11370742-B2 | Process and intermediates for the preparation of bilastine | CYP1B1, CYP2E1, CYP1A1 | ESR1 1214/4885ESR2 1839/4885ALDH1A1 1046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.