Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 14/20 | 0.53 |
| ▸ | MAPK8 | P45983 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21630295 | 0.85 | MAPK10 (0.54) | MAPK10MAPK8KDM4ETHRBGAA | |
| SCHEMBL20027368 | 0.81 | MAPK10 (0.45) | MAPK10MAPK8KDM4ETHRBGAA | |
| SCHEMBL18529459 | 0.78 | KDM4E (0.50) | MAPK10MAPK8KDM4EGAANPC1 | |
| SCHEMBL20027452 | 0.75 | MAPK10 (0.40) | MAPK10MAPK8KDM4ETHRBGAA | |
| Bromide SCHEMBL21630302 | 0.74 | MAPK10 (0.39) | MAPK10MAPK8KDM4EGAANPC1 | |
| SCHEMBL18529461 | 0.72 | MEN1 (0.55) | MAPK10MAPK8KDM4EGAANPC1 | |
| SCHEMBL7787360 | 0.72 | GSK3B (0.44) | THRBGAA | |
| SCHEMBL20027290 | 0.71 | GSK3B (0.38) | MAPK10MAPK8THRBALDH1A1MAPT | |
| SCHEMBL18529484 | 0.70 | GAA (0.45) | MAPK10KDM4EGAANPC1ALDH1A1 | |
| SCHEMBL14645459 | 0.69 | AR (0.50) | MAPK10THRBGAAMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200031778-A1 | NOVEL 5-SUBSTITUTED IMIDAZOLYLMETHYL DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200031778-A1 | NOVEL 5-SUBSTITUTED IMIDAZOLYLMETHYL DERIVATIVES | IPMK, PIP5K1B, PIP5K1C | MAPK10 2374/4885MAPK8 1016/4885KDM4E 608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.