Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 8/20 | 0.48 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LIPE | Q05469 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18529461 | 0.85 | MEN1 (0.55) | KDM4EGAAALDH1A1MEN1KMT2A | |
| SCHEMBL18529484 | 0.81 | GAA (0.45) | KDM4EGAAALDH1A1MEN1KMT2A | |
| SCHEMBL18529450 | 0.79 | MEN1 (0.63) | KDM4EGAAALDH1A1MEN1KMT2A | |
| SCHEMBL21630293 | 0.78 | MAPK10 (0.53) | KDM4EGAAALDH1A1NPSR1MAPK10 | |
| SCHEMBL18499115 | 0.75 | MEN1 (0.69) | KDM4EGAAALDH1A1MEN1KMT2A | |
| SCHEMBL18529456 | 0.75 | ALDH1A1 (0.40) | KDM4EALDH1A1MEN1KMT2AMAPK10 | |
| SCHEMBL18529463 | 0.74 | ALDH1A1 (0.51) | KDM4EGAAALDH1A1MEN1KMT2A | |
| SCHEMBL20471174 | 0.73 | MAPT (0.47) | KDM4EGAAALDH1A1MEN1KMT2A | |
| SCHEMBL21630295 | 0.72 | MAPK10 (0.54) | KDM4EGAAALDH1A1MEN1KMT2A | |
| SCHEMBL12132735 | 0.72 | ALDH1A1 (0.61) | KDM4EALDH1A1MAPTNPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137538-B | Triazole derivatives, intermediates thereof and their use as fungicides | 拜耳作物科学股份公司 | 2021-02-26 | — | — | CN | disclosed |
| US-20200095223-A1 | NOVEL TRIAZOLETHIONE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-03-26 | — | — | US | disclosed |
| US-20200095223-A1 | NOVEL TRIAZOLETHIONE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-03-26 | — | — | US | disclosed |
| US-20180235223-A1 | TRIAZOLE DERIVATIVES, INTERMEDIATES THEREOF AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-08-23 | — | — | US | disclosed |
| WO-2018145933-A1 | TRIAZOLETHIONE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2018-08-16 | — | — | WO | disclosed |
| WO-2018145921-A1 | COMPOSITION FOR CONTROLLING HARMFUL MICROORGANISMS COMPRISING 1 -(PHENOXY-PYRIDINYL)-2-(1,2,4-TRIAZOL-1 -YL)-ETHANOL DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2018-08-16 | — | — | WO | disclosed |
| EP-3334718-A1 | TRIAZOLE DERIVATIVES, INTERMEDIATES THEREOF AND THEIR USE AS FUNGICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2018-06-20 | — | — | EP | disclosed |
| WO-2017029179-A1 | TRIAZOLE DERIVATIVES, INTERMEDIATES THEREOF AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-02-23 | — | — | WO | disclosed |
| WO-2017029179-A1 | TRIAZOLE DERIVATIVES, INTERMEDIATES THEREOF AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180235223-A1 | TRIAZOLE DERIVATIVES, INTERMEDIATES THEREOF AND THEIR USE AS FUNGICIDES | CYP51A1, ERG28, CYP4Z1 | KDM4E 1718/4885GAA 569/4885ALDH1A1 2487/4885 |
| US-20200095223-A1 | NOVEL TRIAZOLETHIONE DERIVATIVES | CYP51A1, SBK3, TST | KDM4E 3224/4885GAA 1518/4885ALDH1A1 2782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.