Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30172138 | 0.86 | LMNA (0.47) | ALDH1A1KMT2ALMNAPKMMAPT | |
| SCHEMBL14645540 | 0.86 | LMNA (0.47) | ALDH1A1KMT2ALMNAPKMMAPT | |
| SCHEMBL18529459 | 0.81 | KDM4E (0.50) | GAANPSR1MAPK10KDM4EALDH1A1 | |
| SCHEMBL18529636 | 0.80 | LMNA (0.44) | ALDH1A1KMT2ALMNAPKMMAPT | |
| SCHEMBL18529651 | 0.79 | ALDH1A1 (0.48) | GAANPSR1MAPK10KDM4EALDH1A1 | |
| SCHEMBL18529650 | 0.78 | CYP3A4 (0.43) | GAANPSR1MAPK10KDM4EALDH1A1 | |
| SCHEMBL19994248 | 0.77 | LMNA (0.48) | KDM4EALDH1A1LMNAPKMMAPT | |
| SCHEMBL9518702 | 0.77 | LMNA (0.56) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL29622955 | 0.77 | LMNA (0.56) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL18529461 | 0.76 | MEN1 (0.55) | GAANPSR1MAPK10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200095223-A1 | NOVEL TRIAZOLETHIONE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-03-26 | — | — | US | disclosed |
| US-20200095223-A1 | NOVEL TRIAZOLETHIONE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-03-26 | — | — | US | disclosed |
| US-20180235223-A1 | TRIAZOLE DERIVATIVES, INTERMEDIATES THEREOF AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-08-23 | — | — | US | disclosed |
| WO-2018145921-A1 | COMPOSITION FOR CONTROLLING HARMFUL MICROORGANISMS COMPRISING 1 -(PHENOXY-PYRIDINYL)-2-(1,2,4-TRIAZOL-1 -YL)-ETHANOL DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2018-08-16 | — | — | WO | disclosed |
| WO-2018145933-A1 | TRIAZOLETHIONE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2018-08-16 | — | — | WO | disclosed |
| EP-3334718-A1 | TRIAZOLE DERIVATIVES, INTERMEDIATES THEREOF AND THEIR USE AS FUNGICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2018-06-20 | — | — | EP | disclosed |
| WO-2017029179-A1 | TRIAZOLE DERIVATIVES, INTERMEDIATES THEREOF AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-02-23 | — | — | WO | disclosed |
| WO-2017029179-A1 | TRIAZOLE DERIVATIVES, INTERMEDIATES THEREOF AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180235223-A1 | TRIAZOLE DERIVATIVES, INTERMEDIATES THEREOF AND THEIR USE AS FUNGICIDES | CYP51A1, ERG28, CYP4Z1 | GAA 569/4885NPSR1 4187/4885MAPK10 3819/4885 |
| US-20200095223-A1 | NOVEL TRIAZOLETHIONE DERIVATIVES | CYP51A1, SBK3, TST | GAA 1518/4885NPSR1 3618/4885MAPK10 2984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.