SCHEMBL21631246

SCHEMBL21631246

CCCCC#Cc1cc2c3c(cccc3c1)C(=O)N(O)C2=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ERCC1 P07992 1/20 0.49
▸ FEN1 P39748 1/20 0.49
▸ ERCC4 Q92889 1/20 0.49
▸ CYP1B1 Q16678 2/20 0.44
▸ TDP1 Q9NUW8 1/20 0.43
▸ BRD1 O95696 1/20 0.40
▸ TAF1 P21675 1/20 0.40
▸ BRPF1 P55201 1/20 0.40
▸ RXFP1 Q9HBX9 1/20 0.39
▸ KMT2A Q03164 4/20 0.37
▸ KDM4E B2RXH2 3/20 0.37
▸ ALDH1A1 P00352 3/20 0.37
▸ MEN1 O00255 2/20 0.37
▸ POLB P06746 2/20 0.37
▸ HPGD P15428 1/20 0.37
▸ HSD17B10 Q99714 1/20 0.37
▸ TNK2 Q07912 1/20 0.37
▸ CYP1A2 P05177 1/20 0.37
▸ TNNI3 P19429 1/20 0.37
▸ MAPK1 P28482 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29713417 1.00 ERCC1 (0.49) ERCC1FEN1ERCC4CYP1B1TDP1
SCHEMBL21650724 0.93 ERCC1 (0.51) ERCC1FEN1ERCC4CYP1B1TDP1
SCHEMBL20801123 0.86 TDP1 (0.50) CYP1B1TDP1BRD1TAF1BRPF1
SCHEMBL21631279 0.81 TYMS (0.45) CYP1B1TDP1TNK2
SCHEMBL29713399 0.81 TYMS (0.45) CYP1B1TDP1TNK2
SCHEMBL20801124 0.79 TDP1 (0.43) CYP1B1TDP1BRD1TAF1BRPF1
SCHEMBL18069180 0.76 KMT2A (0.48) ERCC1FEN1ERCC4CYP1B1TDP1
SCHEMBL18069149 0.76 TDP1 (0.42) CYP1B1TDP1BRD1TAF1BRPF1
SCHEMBL21650723 0.74 TYMS (0.47) CYP1B1
SCHEMBL18069139 0.72 TDP1 (0.39) CYP1B1TDP1BRD1TAF1BRPF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11150555-B2 Photoacid generator and chemically amplified positive-type photoresist composition for thick film comprising the same LG CHEM, LTD. (KR) 2021-10-19 — — US disclosed
US-11150555-B2 Photoacid generator and chemically amplified positive-type photoresist composition for thick film comprising the same LG CHEM, LTD. (KR) 2021-10-19 — — US disclosed
US-20200033724-A1 PHOTOACID GENERATOR AND CHEMICALLY AMPLIFIED POSITIVE-TYPE PHOTORESIST COMPOSITION FOR THICK FILM COMPRISING THE SAME LG CHEM, LTD. (KR) 2020-01-30 — — US disclosed
US-20200033724-A1 PHOTOACID GENERATOR AND CHEMICALLY AMPLIFIED POSITIVE-TYPE PHOTORESIST COMPOSITION FOR THICK FILM COMPRISING THE SAME LG CHEM, LTD. (KR) 2020-01-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200033724-A1 PHOTOACID GENERATOR AND CHEMICALLY AMPLIFIED POSITIVE-TYPE PHOTORESIST COMPOSITION FOR THICK FILM COMPRISING THE SAME ASIC1, PPA1, ATP6AP1 ERCC1 1727/4885FEN1 2259/4885ERCC4 2449/4885
US-11150555-B2 Photoacid generator and chemically amplified positive-type photoresist composition for thick film comprising the same ASIC1, PPA1, ATP6AP1 ERCC1 1727/4885FEN1 2259/4885ERCC4 2449/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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