SCHEMBL2163258

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12403865	0.86	MMP2 (0.47)	RAD51MEN1KMT2ARAB9AMAPT
	SCHEMBL2163017	0.83	MEN1 (0.45)	RAD51MEN1KMT2ARAB9AMAPT
	SCHEMBL484211	0.83	ADORA2A (0.58)	RAD51MEN1KMT2ARAB9AMAPT
	SCHEMBL2163050	0.81	RAD51 (0.57)	RAD51MEN1KMT2ARAB9AADORA2A
	SCHEMBL20816315	0.76	RAD51 (1.00)	RAD51MEN1KMT2ARAB9AMAPT
	SCHEMBL2163042	0.72	ADORA2A (0.53)	RAD51MEN1KMT2ARAB9AMAPT
	SCHEMBL2162677	0.72	NPC1 (0.53)	MEN1KMT2ARAB9AMAPTTDP1
	Bromide SCHEMBL2164327	0.71	ADORA2A (0.52)	RAD51MEN1KMT2ARAB9AMAPT
	SCHEMBL2162770	0.71	MAPT (0.37)	MEN1KMT2ARAB9AMAPTTDP1
	SCHEMBL15602823	0.69	RAB9A (0.68)	RAD51MEN1KMT2ARAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.