Propene

Propene

SCHEMBL2163341

C=C(CO)C(=O)OCCOC(=O)C(=C)CO.C=CC.C=CC

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.39
TSHR P16473 7/20 0.35
ALDH1A1 P00352 3/20 0.35
TP53 P04637 2/20 0.35
HIF1A Q16665 2/20 0.35
HSD17B10 Q99714 1/20 0.35
HPGD P15428 1/20 0.32
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propene SCHEMBL2165032 0.92 TSHR (0.47) THRBTSHRHPGD
Propene SCHEMBL2165018 0.81 THRB (0.38) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL26129017 0.80 TSHR (0.44) THRBTSHRALDH1A1HPGD
SCHEMBL52703 0.80 TSHR (0.44) THRBTSHRALDH1A1HPGD
SCHEMBL5080593 0.79 TSHR (0.44) THRBTSHR
SCHEMBL824127 0.79 THRB (0.66) THRBTSHRALDH1A1TP53HIF1A
Acrylic Acid SCHEMBL9248645 0.79 HCAR2 (0.43) THRBTSHRALDH1A1TP53HIF1A
Propene SCHEMBL11112032 0.77 THRB (0.63) THRBTSHRALDH1A1TP53HIF1A
Propene SCHEMBL672400 0.77 THRB (0.63) THRBTSHRALDH1A1TP53HIF1A
Propene SCHEMBL7154370 0.77 THRB (0.63) THRBTSHRALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2119734-B1 COPOLYMER AND USE THEREOF DAINICHISEIKA COLOR CHEM (JP) 2013-03-27 EP disclosed
US-7985796-B2 Copolymer and use thereof DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2011-07-26 US disclosed
US-20100120974-A1 COPOLYMER AND USE THEREOF DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2010-05-13 US disclosed
EP-2119734-A1 COPOLYMER AND USE THEREOF Dainichiseika Color & Chemicals Mfg. Co., Ltd. (JP) 2009-11-18 EP disclosed