SCHEMBL2163401

SCHEMBL2163401

CCCCCCC/C=C/[C]=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 4/20 0.54
TRPV1 Q8NER1 1/20 0.54
TSHR P16473 1/20 0.48
TERT O14746 3/20 0.47
PTPN1 P18031 3/20 0.47
PPARG P37231 3/20 0.47
PPARD Q03181 3/20 0.47
PPARA Q07869 3/20 0.47
CYP1A2 P05177 2/20 0.47
MAPT P10636 2/20 0.47
CYP2C19 P33261 2/20 0.47
BLM P54132 2/20 0.47
HSD17B10 Q99714 2/20 0.47
FABP4 P15090 2/20 0.47
KMT2A Q03164 2/20 0.47
GMNN O75496 1/20 0.47
USP2 O75604 1/20 0.47
LMNA P02545 1/20 0.47
POLB P06746 1/20 0.47
CYP2C9 P11712 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL158907 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL2163660 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL16431159 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL910497 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL548514 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL548521 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL1240474 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL158906 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL9696115 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL415112 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1116715-B1 Tetramic acid derivatives useful in medicines and foodstuffs JUNG GUENTHER PROF DR (DE) 2004-10-06 EP claimed
WO-2001051465-A1 TETRAMIC ACID DERIVATIVES FOR USE IN MEDICINE AND FOOD TECHNOLOGY STRACKE, FRIEDRICH (DE) 2001-07-19 WO claimed
EP-1116715-A1 Tetramic acid derivatives useful in medicines and foodstuffs Jung, Günther, Prof. Dr. (DE) 2001-07-18 EP claimed
CN-103958692-B Genetically engineered microorganisms comprising 4-hydroxybenzoyl-COA thioesterases and methods of using the same 艾克森美孚研究与工程公司 2020-02-21 CN disclosed
CN-105296511-A PRODUCTION OF DHA AND OTHER LC-PUFAS IN PLANTS DOW AGROSCIENCES LLC 2016-02-03 CN disclosed
CN-103080319-B Production of DHA and other LC-PUFAs in plants DOW AGROSCIENCES LLC (US) 2015-11-25 CN disclosed
CN-103014027-B Method for optimizing synthetic route of fatty acid in escherichia coli UNIV SHANGHAI JIAOTONG 2014-12-10 CN disclosed
CN-102899281-B System for efficiently producing aliphatic acid by escherichia coli and construction method thereof SHANGHAI JIAO TONG UNIVERSITY (CN) 2014-10-15 CN disclosed
CN-101389213-B Pufa polyketide synthase systems and uses thereof MARTEK BIOSCIENCES CORP 2014-05-28 CN disclosed
US-7985572-B2 Modified nitrilases and their use in methods for the production of carboxylic acids BASF SE (DE) 2011-07-26 US disclosed
EP-2240449-A1 NOVEL ANTI-INFECTIOUS DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND USES OF SAID DERIVATIVES IN TREATMENT Centre National de la Recherche Scientifique - CNRS (FR) 2010-10-20 EP disclosed
WO-1994001113-A1 OXYTOCIN ANTAGONIST OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1994-01-20 WO disclosed
US-5225402-A Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-07-06 US disclosed
EP-0382185-A2 Carbostyril derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1990-08-16 EP disclosed
US-4831135-A ANTITUMOR AGENTS, ANTIBIOTICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1989-05-16 US disclosed
US-4665201-A ANTITUMOR AGENTS SUNTORY, LIMITED (JP) 1987-05-12 US disclosed
EP-0080570-B1 AILANTHONE DERIVATIVES SUNTORY LIMITED (JP) 1986-12-17 EP disclosed
US-4438277-A Hydronaphthalene derivatives SANKYO COMPANY, LIMITED (JP) 1984-03-20 US disclosed
EP-0080570-A2 Ailanthone derivatives SUNTORY LIMITED (JP) 1983-06-08 EP disclosed
US-4361515-A Antihyperlipemic dihydro-ML-236B derivatives, their preparation and use SANKYO COMPANY, LIMITED (JP) 1982-11-30 US disclosed