SCHEMBL415112

SCHEMBL415112

CCCCCCCCCCCCCCCCCC=C[C]=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 4/20 0.54
TRPV1 Q8NER1 1/20 0.54
TSHR P16473 1/20 0.48
TERT O14746 3/20 0.47
PTPN1 P18031 3/20 0.47
PPARG P37231 3/20 0.47
PPARD Q03181 3/20 0.47
PPARA Q07869 3/20 0.47
CYP1A2 P05177 2/20 0.47
MAPT P10636 2/20 0.47
CYP2C19 P33261 2/20 0.47
BLM P54132 2/20 0.47
HSD17B10 Q99714 2/20 0.47
FABP4 P15090 2/20 0.47
KMT2A Q03164 2/20 0.47
GMNN O75496 1/20 0.47
USP2 O75604 1/20 0.47
LMNA P02545 1/20 0.47
POLB P06746 1/20 0.47
CYP2C9 P11712 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL158907 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL2163660 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL2163401 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL16431159 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL910497 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL548514 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL548521 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL1240474 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL158906 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL9696115 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 349 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107074762-B Use of esters of N-acylated derivatives of amino acids and polyols as anti-ageing agents for human skin 化工产品开发公司SEPPIC 2021-06-15 CN claimed
EP-3212615-B1 USE OF ESTERS OF N-ACYLATED DERIVATIVES OF AMINO ACIDS AND POLYOLS AS AN ANTI-AGEING AGENT FOR HUMAN SKIN SOC DEXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2018-08-29 EP claimed
EP-2771318-B1 NOVEL ESTERS OF N-ACYL DERIVATIVES OF AMINO ACIDS AND DIOLS, METHOD FOR PREPARING SAME, AND USE THEREOF IN COSMETICS AND AS A DRUG SOC DEXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2018-06-06 EP claimed
US-20170312205-A1 USE OF ESTERS OF N-ACYLATED DERIVATIVES OF AMINO ACIDS AND POLYOLS AS AN ANTI-AGEING AGENT FOR HUMAN SKIN SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2017-11-02 US claimed
US-9567290-B2 Esters of N-acyl derivatives of amino acids and diols, method for preparing same, and use thereof in cosmetics and as a drug SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2017-02-14 US claimed
US-8906409-B2 Acoustically sensitive drug delivery particles comprising non-lamellar forming phosphatidylcholine EPITARGET AS (DE) 2014-12-09 US claimed
US-20140288144-A1 NOVEL ESTERS OF N-ACYL DERIVATIVES OF AMINO ACIDS AND DIOLS, METHOD FOR PREPARING SAME, AND USE THEREOF IN COSMETICS AND AS A DRUG SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2014-09-25 US claimed
US-8765172-B2 Acoustically sensitive drug delivery particles comprising non-lamellar forming lipids EPITARGET AS (NO) 2014-07-01 US claimed
US-20130017248-A1 Cationic Liposomes And Method of Use Life Technologies Corporation (US) 2013-01-17 US claimed
US-20120189689-A1 ACOUSTICALLY SENSITIVE DRUG DELIVERY PARTICLES COMPRISING NON-LAMELLAR FORMING PHOSPHATIDYLCHOLINE EPITARGET AS (NO) 2012-07-26 US claimed
WO-2001042405-A2 WATER SOLUBLE VEGETABLE OIL ESTERS FOR INDUSTRIAL APPLICATIONS CARGILL INCORPORATED (US) 2001-06-14 WO claimed
US-20010002257-A1 Composition comprising a lipoamino acid and the constituents of a tannin-rich plant extract, and cosmetic use thereof STOLZ CORINNE (FR) 2001-05-31 US claimed
EP-0986570-A1 GEMCITABINE DERIVATIVES NORSK HYDRO ASA (NO) 2000-03-22 EP claimed
WO-1998032762-A1 GEMCITABINE DERIVATIVES NORSK HYDRO ASA (NO) 1998-07-30 WO claimed
EP-0842185-A1 IMPROVED THERAPEUTIC AGENTS NORSK HYDRO a.s. (NO) 1998-05-20 EP claimed
WO-1997005154-A1 IMPROVED THERAPEUTIC AGENTS NORSK HYDRO ASA (NO) 1997-02-13 WO claimed
EP-0349579-B1 LIPID VESICLES FORMED OF SURFACTANTS AND STEROIDS MICRO VESICULAR SYSTEMS, INC. (US) 1992-01-08 EP claimed
US-4917951-A POLYOXYETHYLENE ETHERS OR AMINES MICRO-PAK, INC. (US) 1990-04-17 US claimed
EP-0349579-A1 LIPID VESICLES FORMED OF SURFACTANTS AND STEROIDS. MICRO VESICULAR SYSTEMS (US) 1990-01-10 EP claimed
WO-1988006882-A1 LIPID VESICLES FORMED OF SURFACTANTS AND STEROIDS MICRO VESICULAR SYSTEMS, INC. (US) 1988-09-22 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170312205-A1 USE OF ESTERS OF N-ACYLATED DERIVATIVES OF AMINO ACIDS AND POLYOLS AS AN ANTI-AGEING AGENT FOR HUMAN SKIN LPO, ARG2, CUTA FAAH 304/4885TRPV1 2280/4885TSHR 4158/4885
US-20010002257-A1 Composition comprising a lipoamino acid and the constituents of a tannin-rich plant extract, and cosmetic use thereof LIPC, PLIN1, LRAT FAAH 33/4885TRPV1 1068/4885TSHR 2099/4885
US-20140288144-A1 NOVEL ESTERS OF N-ACYL DERIVATIVES OF AMINO ACIDS AND DIOLS, METHOD FOR PREPARING SAME, AND USE THEREOF IN COSMETICS AND AS A DRUG DAO, ACOX3, IL4I1 FAAH 695/4885TRPV1 2495/4885TSHR 1787/4885
US-20130017248-A1 Cationic Liposomes And Method of Use CLTB, AGBL2, CLTC FAAH 3441/4885TRPV1 3914/4885TSHR 3348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.