Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 7/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL548631 | 0.78 | GRIA3 (0.53) | VNN1TRPV4HCAR3KDM1AGRIA3 | |
| SCHEMBL3116608 | 0.72 | TTR (0.43) | VNN1NPC1RAB9APRMT5WDR77 | |
| SCHEMBL2779111 | 0.72 | HDAC6 (0.32) | GRIA3GRIA4 | |
| SCHEMBL3102517 | 0.72 | TTR (0.47) | VNN1KMT2AKDM1A | |
| SCHEMBL2776562 | 0.70 | TDP1 (0.44) | NPC1RAB9AHCAR3KMT2APOLB | |
| SCHEMBL15019261 | 0.69 | TSHR (0.40) | KMT2A | |
| SCHEMBL21162194 | 0.69 | ELOVL6 (0.53) | VNN1ELOVL6POLB | |
| SCHEMBL3809628 | 0.68 | F10 (0.46) | VNN1NPC1RAB9AKMT2AKDM1A | |
| SCHEMBL1308010 | 0.68 | HPGD (0.46) | VNN1NPC1RAB9AKMT2AKDM1A | |
| SCHEMBL10032960 | 0.67 | GRIA3 (0.60) | HCAR3GRIA3GRIA4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3829567-A1 | CLINICAL METHODS AND PHARMACEUTICAL COMPOSITIONS EMPLOYING AMPA RECEPTOR ANTAGONISTS TO TREAT GLIOBLASTOMA AND OTHER CANCERS | With Great Power, LLC (US) | 2021-06-09 | — | — | EP | disclosed |
| WO-2020023800-A1 | CLINICAL METHODS AND PHARMACEUTICAL COMPOSITIONS EMPLOYING AMPA RECEPTOR ANTAGONISTS TO TREAT GLIOBLASTOMA AND OTHER CANCERS | WITH GREAT POWER, LLC (US) | 2020-01-30 | — | — | WO | disclosed |