SCHEMBL21634149

SCHEMBL21634149

CCSc1n[nH]c(C(C)C)n1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.47
HPGD P15428 2/20 0.47
MAPT P10636 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
ADORA2A P29274 1/20 0.43
ADORA1 P30542 1/20 0.43
ALPL P05186 1/20 0.43
ALDH1A1 P00352 2/20 0.40
POLB P06746 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.38
PKM P14618 1/20 0.38
GRK6 P43250 1/20 0.38
HTT P42858 1/20 0.37
GRM2 Q14416 2/20 0.35
GRM3 Q14832 2/20 0.35
HSP90AA1 P07900 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21934979 0.67 ADORA2A (0.33) LMNAHPGDADORA2AADORA1
SCHEMBL4752884 0.66
SCHEMBL12039946 0.66 HSP90AA1 (0.54) LMNAMAPTADORA2AADORA1ALDH1A1
SCHEMBL11511782 0.64 DCUN1D1 (0.67) HPGDALPLALDH1A1SMN1; SMN2GRK6
SCHEMBL18922260 0.64
SCHEMBL21934980 0.64 ADORA2A (0.37) LMNAHPGDMAPTL3MBTL1ADORA2A
SCHEMBL15999332 0.62 MEN1 (0.41) ADORA2AADORA1SMN1; SMN2HTT
SCHEMBL11512748 0.62 RAB9A (0.63) HPGDALPLALDH1A1POLBSMN1; SMN2
SCHEMBL13150042 0.61 ADORA2A (0.32) ADORA2AADORA1
SCHEMBL19219030 0.61 CTH (0.33) LMNAMAPTADORA2AADORA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4722199-A1 AZOLE COMPOUND, METHOD FOR SYNTHESIZING SAID AZOLE COMPOUND, AND USE THEREOF SHIKOKU CHEMICALS CORPORATION (JP) 2026-04-08 EP disclosed
WO-2024247919-A1 AZOLE COMPOUND, METHOD FOR SYNTHESIZING SAID AZOLE COMPOUND, AND USE THEREOF 四国化成工業株式会社 2024-12-05 WO disclosed
US-11680076-B2 Triazole silane compound, method for synthesizing said compound and use thereof SHIKOKU CHEMICALS CORPORATION (JP) 2023-06-20 US disclosed
CN-110475782-B Triazole silane compound, method for synthesizing the compound, and use thereof 四国化成工业株式会社 2022-05-17 CN disclosed
EP-3608327-B1 TRIAZOLE SILANE COMPOUND, METHOD FOR SYNTHESIZING SAID COMPOUND AND USE THEREOF SHIKOKU CHEM (JP) 2022-05-04 EP disclosed
EP-3608327-A1 TRIAZOLE SILANE COMPOUND, METHOD FOR SYNTHESIZING SAID COMPOUND AND USE THEREOF Shikoku Chemicals Corporation (JP) 2020-02-12 EP disclosed
US-20200031852-A1 TRIAZOLE SILANE COMPOUND, METHOD FOR SYNTHESIZING SAID COMPOUND AND USE THEREOF SHIKOKU CHEMICALS CORPORATION (JP) 2020-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11680076-B2 Triazole silane compound, method for synthesizing said compound and use thereof CYP51A1, TLK2, SIK2 LMNA 3218/4885HPGD 3199/4885MAPT 2147/4885
US-20200031852-A1 TRIAZOLE SILANE COMPOUND, METHOD FOR SYNTHESIZING SAID COMPOUND AND USE THEREOF SEPTIN8, SIK2, CYP51A1 LMNA 3722/4885HPGD 3106/4885MAPT 2836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.