SCHEMBL21634159

SCHEMBL21634159

CCCCCCSc1nc(N)n[nH]1

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.57
ALDH1A1 P00352 2/20 0.57
LMNA P02545 1/20 0.57
MAPT P10636 1/20 0.57
HPGD P15428 1/20 0.57
SCN9A Q15858 2/20 0.50
SCN5A Q14524 1/20 0.50
XDH P47989 1/20 0.46
GPR84 Q9NQS5 8/20 0.44
CXCR1 P25024 1/20 0.43
CXCR2 P25025 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11584539 0.93 SMN1; SMN2 (0.47) SMN1; SMN2ALDH1A1LMNAMAPTHPGD
SCHEMBL8406500 0.92 SMN1; SMN2 (0.49) SMN1; SMN2ALDH1A1LMNAMAPTHPGD
SCHEMBL8404275 0.91 SMN1; SMN2 (0.48) SMN1; SMN2ALDH1A1LMNAMAPTHPGD
SCHEMBL8404273 0.91 SMN1; SMN2 (0.48) SMN1; SMN2ALDH1A1LMNAMAPTHPGD
SCHEMBL8406974 0.91 SMN1; SMN2 (0.48) SMN1; SMN2ALDH1A1LMNAMAPTHPGD
SCHEMBL11584813 0.85 KMT2A (0.40) SMN1; SMN2ALDH1A1LMNAMAPTHPGD
SCHEMBL11511598 0.81 SMN1; SMN2 (0.68) SMN1; SMN2ALDH1A1LMNAMAPTHPGD
SCHEMBL17726979 0.80 ALDH1A1 (0.37) SMN1; SMN2ALDH1A1LMNAMAPTHPGD
SCHEMBL17726987 0.80 ALDH1A1 (0.37) SMN1; SMN2ALDH1A1LMNAMAPTHPGD
SCHEMBL17727027 0.79 SMN1; SMN2 (0.36) SMN1; SMN2ALDH1A1LMNAMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4722199-A1 AZOLE COMPOUND, METHOD FOR SYNTHESIZING SAID AZOLE COMPOUND, AND USE THEREOF SHIKOKU CHEMICALS CORPORATION (JP) 2026-04-08 EP disclosed
WO-2024247919-A1 AZOLE COMPOUND, METHOD FOR SYNTHESIZING SAID AZOLE COMPOUND, AND USE THEREOF 四国化成工業株式会社 2024-12-05 WO disclosed
US-11680076-B2 Triazole silane compound, method for synthesizing said compound and use thereof SHIKOKU CHEMICALS CORPORATION (JP) 2023-06-20 US disclosed
CN-110475782-B Triazole silane compound, method for synthesizing the compound, and use thereof 四国化成工业株式会社 2022-05-17 CN disclosed
EP-3608327-B1 TRIAZOLE SILANE COMPOUND, METHOD FOR SYNTHESIZING SAID COMPOUND AND USE THEREOF SHIKOKU CHEM (JP) 2022-05-04 EP disclosed
EP-3608327-A1 TRIAZOLE SILANE COMPOUND, METHOD FOR SYNTHESIZING SAID COMPOUND AND USE THEREOF Shikoku Chemicals Corporation (JP) 2020-02-12 EP disclosed
US-20200031852-A1 TRIAZOLE SILANE COMPOUND, METHOD FOR SYNTHESIZING SAID COMPOUND AND USE THEREOF SHIKOKU CHEMICALS CORPORATION (JP) 2020-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11680076-B2 Triazole silane compound, method for synthesizing said compound and use thereof CYP51A1, TLK2, SIK2 SMN1; SMN2 4822/4885ALDH1A1 1995/4885LMNA 3218/4885
US-20200031852-A1 TRIAZOLE SILANE COMPOUND, METHOD FOR SYNTHESIZING SAID COMPOUND AND USE THEREOF SEPTIN8, SIK2, CYP51A1 SMN1; SMN2 4784/4885ALDH1A1 1887/4885LMNA 3722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.