SCHEMBL8404273

SCHEMBL8404273

CCCCCCCCSCCSc1nc(N)n[nH]1

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.48
ALDH1A1 P00352 2/20 0.48
LMNA P02545 1/20 0.48
MAPT P10636 1/20 0.48
HPGD P15428 1/20 0.48
SCN9A Q15858 2/20 0.43
SCN5A Q14524 1/20 0.43
XDH P47989 1/20 0.39
GPR84 Q9NQS5 8/20 0.38
CXCR1 P25024 1/20 0.36
CXCR2 P25025 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8404275 1.00 SMN1; SMN2 (0.48) SMN1; SMN2ALDH1A1LMNAMAPTHPGD
SCHEMBL8406974 1.00 SMN1; SMN2 (0.48) SMN1; SMN2ALDH1A1LMNAMAPTHPGD
SCHEMBL8406500 0.92 SMN1; SMN2 (0.49) SMN1; SMN2ALDH1A1LMNAMAPTHPGD
SCHEMBL21634159 0.91 SMN1; SMN2 (0.57) SMN1; SMN2ALDH1A1LMNAMAPTHPGD
SCHEMBL11584539 0.84 SMN1; SMN2 (0.47) SMN1; SMN2ALDH1A1LMNAMAPTHPGD
SCHEMBL8519180 0.74 SMN1; SMN2 (0.42) SMN1; SMN2ALDH1A1LMNAMAPTHPGD
SCHEMBL11584118 0.73
SCHEMBL11511598 0.72 SMN1; SMN2 (0.68) SMN1; SMN2ALDH1A1LMNAMAPTHPGD
SCHEMBL10966224 0.70 ALDH1A1 (0.50) SMN1; SMN2ALDH1A1LMNAMAPTHPGD
SCHEMBL21634168 0.70 SMN1; SMN2 (0.55) SMN1; SMN2ALDH1A1LMNAMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0573373-B1 Tone control of photographic silver images EASTMAN KODAK CO (US) 1999-07-14 EP disclosed
EP-0575262-B1 Radiographic elements with improved covering power EASTMAN KODAK CO (US) 1999-07-07 EP disclosed
US-5314790-A Tetrazoles or triazoles EASTMAN KODAK COMPANY (US) 1994-05-24 US disclosed
US-5292627-A Azole to modify tone EASTMAN KODAK COMPANY (US) 1994-03-08 US disclosed
US-5292631-A Radiographic elements with improved covering power EASTMAN KODAK COMPANY (US) 1994-03-08 US disclosed
EP-0575262-A2 Radiographic elements with improved covering power EASTMAN KODAK COMPANY (US) 1993-12-22 EP disclosed
EP-0573373-A2 Tone control of photographic silver images EASTMAN KODAK COMPANY (US) 1993-12-08 EP disclosed