SCHEMBL21634367

SCHEMBL21634367

OCCNCCNCc1cccc(OCc2ccccc2)c1

nearest known ligand 0.74

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
BCHE P06276 9/20 0.72
CYP4F2 P78329 1/20 0.61
CYP4A11 Q02928 1/20 0.61
MAPK1 P28482 1/20 0.60
LMNA P02545 1/20 0.59
MEN1 O00255 2/20 0.57
ALDH1A1 P00352 2/20 0.57
KMT2A Q03164 2/20 0.57
L3MBTL1 Q9Y468 2/20 0.57
KDM4E B2RXH2 1/20 0.57
GAA P10253 1/20 0.57
MAPT P10636 1/20 0.57
THRB P10828 1/20 0.57
PKM P14618 1/20 0.57
RAB9A P51151 1/20 0.57
BLM P54132 1/20 0.57
TDP1 Q9NUW8 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30821677 1.00 BCHE (0.72) BCHECYP4F2CYP4A11MAPK1LMNA
SCHEMBL10011367 0.97 BCHE (0.76) BCHECYP4F2CYP4A11MAPK1MEN1
SCHEMBL30821452 0.97 BCHE (0.76) BCHECYP4F2CYP4A11MAPK1MEN1
SCHEMBL21634358 0.89 SMN1; SMN2 (0.64) BCHELMNAMEN1ALDH1A1KMT2A
SCHEMBL21634276 0.89 MEN1 (0.62) BCHEMAPK1LMNAMEN1KMT2A
SCHEMBL30821480 0.89 SMN1; SMN2 (0.64) BCHELMNAMEN1ALDH1A1KMT2A
SCHEMBL23120424 0.89 BCHE (0.77) BCHECYP4F2CYP4A11MAPK1MEN1
SCHEMBL14704473 0.87 BCHE (0.60) BCHECYP4F2CYP4A11LMNARAB9A
SCHEMBL21634318 0.86 SMN1; SMN2 (0.67) BCHELMNAMEN1ALDH1A1KMT2A
SCHEMBL21634323 0.86 MEN1 (0.65) BCHEMAPK1LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210163399-A1 NOVEL P62 LIGAND COMPOUND, AND COMPOSITION FOR PREVENTING, AMELIORATING OR TREATING PROTEINOPATHIES COMPRING THE SAME PROTECH CO., LTD. (KR) 2021-06-03 US claimed
EP-3828163-A1 NOVEL P62 LIGAND COMPOUND, AND COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING PROTEINOPATHIES COMPRISING SAME Protech Co., Ltd. (KR) 2021-06-02 EP claimed
WO-2020022784-A1 NOVEL P62 LIGAND COMPOUND, AND COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING PROTEINOPATHIES COMPRISING SAME 주식회사 프로텍바이오 2020-01-30 WO claimed
US-12427346-B2 P62 ligand compound, and composition for preventing, ameliorating or treating proteinopathies comprising the same AUTOTAC INC. (KR) 2025-09-30 US disclosed
CN-112424160-B Novel P62 ligand compound and composition for preventing, improving or treating protein conformational diseases comprising the same 奧土择破利悟株式会社 2024-03-08 CN disclosed
US-20210163399-A1 NOVEL P62 LIGAND COMPOUND, AND COMPOSITION FOR PREVENTING, AMELIORATING OR TREATING PROTEINOPATHIES COMPRING THE SAME PROTECH CO., LTD. (KR) 2021-06-03 US disclosed
EP-3828163-A1 NOVEL P62 LIGAND COMPOUND, AND COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING PROTEINOPATHIES COMPRISING SAME Protech Co., Ltd. (KR) 2021-06-02 EP disclosed
WO-2020022784-A1 NOVEL P62 LIGAND COMPOUND, AND COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING PROTEINOPATHIES COMPRISING SAME 주식회사 프로텍바이오 2020-01-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210163399-A1 NOVEL P62 LIGAND COMPOUND, AND COMPOSITION FOR PREVENTING, AMELIORATING OR TREATING PROTEINOPATHIES COMPRING THE SAME SQSTM1, ATG7, BECN1 BCHE 3322/4885CYP4F2 4355/4885CYP4A11 3690/4885
US-12427346-B2 P62 ligand compound, and composition for preventing, ameliorating or treating proteinopathies comprising the same SQSTM1, ATG7, BECN1 BCHE 3594/4885CYP4F2 4416/4885CYP4A11 3826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.