SCHEMBL21634730

SCHEMBL21634730

CC(C)(C)OC(=O)N1CCC2(CC1)CSC2

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
HPGD P15428 1/20 0.43
EPHX2 P34913 1/20 0.42
GPR119 Q8TDV5 5/20 0.42
SCD5 Q86SK9 1/20 0.42
RECQL P46063 1/20 0.41
EPHX1 P07099 1/20 0.41
CYP11B2 P19099 1/20 0.41
ACACB O00763 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25485645 0.90 SCD5 (0.48) USP2SMN1; SMN2HPGDGPR119SCD5
SCHEMBL16580040 0.89 USP2 (0.46) USP2SMN1; SMN2HPGDEPHX2GPR119
SCHEMBL346995 0.85 USP2 (0.56) USP2SMN1; SMN2HPGDEPHX2GPR119
SCHEMBL24906944 0.85 USP2 (0.49) USP2SMN1; SMN2HPGDEPHX2GPR119
SCHEMBL21358370 0.82 USP2 (0.44) USP2SMN1; SMN2HPGDEPHX2SCD5
SCHEMBL20937613 0.82 USP2 (0.53) USP2SMN1; SMN2HPGDEPHX2GPR119
SCHEMBL933177 0.82 USP2 (0.53) USP2SMN1; SMN2HPGDEPHX2GPR119
SCHEMBL15769706 0.81 USP2 (0.51) USP2SMN1; SMN2HPGDEPHX2GPR119
SCHEMBL20937760 0.81 USP2 (0.51) USP2SMN1; SMN2HPGDEPHX2GPR119
SCHEMBL1779347 0.81 USP2 (0.51) USP2SMN1; SMN2HPGDEPHX2GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12109203-B2 Substituted oxazolidinones for the treatment of mammalian infections ZYDUS LIFESCIENCES LIMITED (IN) 2024-10-08 US disclosed
WO-2020021468-A1 SUBSTITUTED OXAZOLIDINONES FOR THE TREATMENT OF MAMMALIAN INFECTIONS CADILA HEALTHCARE LIMITED (IN) 2020-01-30 WO disclosed
WO-2020021468-A1 SUBSTITUTED OXAZOLIDINONES FOR THE TREATMENT OF MAMMALIAN INFECTIONS CADILA HEALTHCARE LIMITED (IN) 2020-01-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12109203-B2 Substituted oxazolidinones for the treatment of mammalian infections OXA1L, IL4I1, PEPD USP2 4551/4885SMN1; SMN2 2025/4885HPGD 489/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.