SCHEMBL21634786 — predicted protein targets

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	MAOA	P21397	8/20	0.40

▸	MAOB	P27338	7/20	0.36

▸	CALML3	P27482	3/20	0.35

▸	CYP2E1	P05181	1/20	0.34

▸	F10	P00742	6/20	0.34

▸	LMNA	P02545	1/20	0.33

▸	PTGS1	P23219	1/20	0.33

▸	SDHA	P31040	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL21634783	0.94	MAOA (0.38)	MAOAMAOBCALML3CYP2E1F10
SCHEMBL2897203	0.81	CALML3 (0.42)	MAOAMAOBCALML3F10LMNA
SCHEMBL21634693	0.81	MAOA (0.54)	MAOAMAOBCALML3CYP2E1F10
SCHEMBL21634712	0.78	MAOA (0.49)	MAOAMAOBCALML3F10LMNA
SCHEMBL21634709	0.78	MAOA (0.49)	MAOAMAOBCALML3F10LMNA
SCHEMBL21690972	0.78	MAOB (0.35)	MAOAMAOBCALML3CYP2E1F10
SCHEMBL21635031	0.78	MAOA (0.51)	MAOAMAOBCALML3F10LMNA
SCHEMBL21634710	0.77	MAOA (0.47)	MAOAMAOBCALML3F10LMNA
SCHEMBL6625397	0.76	F10 (0.53)	MAOAMAOBCALML3F10LMNA
SCHEMBL20333808	0.75	MAOA (0.48)	MAOAMAOBCALML3F10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2020021468-A1	SUBSTITUTED OXAZOLIDINONES FOR THE TREATMENT OF MAMMALIAN INFECTIONS	CADILA HEALTHCARE LIMITED (IN)	2020-01-30	—	—	WO	disclosed