SCHEMBL6625397

SCHEMBL6625397

O=C1OC(CN(C(=O)O)c2ccon2)CN1c1ccc(N2CCNCC2)c(F)c1

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
F10 P00742 7/20 0.53
MAOB P27338 10/20 0.51
MAOA P21397 5/20 0.47
CALML3 P27482 2/20 0.47
LMNA P02545 1/20 0.47
PTGS1 P23219 1/20 0.47
SDHA P31040 1/20 0.47
KCNH2 Q12809 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2897203 0.82 CALML3 (0.42) F10MAOBMAOACALML3LMNA
SCHEMBL21999243 0.80 MAOB (0.57) F10MAOBMAOACALML3LMNA
SCHEMBL2088562 0.80 F10 (0.58) F10MAOBMAOACALML3LMNA
SCHEMBL3331210 0.79 CALML3 (0.53) MAOBMAOACALML3
SCHEMBL3328449 0.79 CALML3 (0.53) MAOBMAOACALML3
SCHEMBL28757341 0.79 MAOB (0.61) F10MAOBMAOACALML3LMNA
SCHEMBL3197103 0.79 F10 (0.65) F10MAOBMAOACALML3LMNA
SCHEMBL6629866 0.79 F10 (0.65) F10MAOBMAOACALML3LMNA
SCHEMBL6110851 0.78 MAOA (0.62) F10MAOBMAOACALML3LMNA
SCHEMBL6111122 0.78 F10 (0.52) F10MAOBMAOACALML3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040147545-A1 Derivatives of oxazolidinones as antibacterial agents LABORATORIOS VITA, S.A. (ES) 2004-07-29 US disclosed
EP-1401834-A1 NEW DERIVATIVES OF OXAZOLIDINONES AS ANTIBACTERIAL AGENTS LABORATORIOS VITA, S.A. (ES) 2004-03-31 EP disclosed
WO-2003002560-A1 NEW DERIVATIVES OF OXAZOLIDINONES AS ANTIBACTERIAL AGENTS LABORATORIOS VITA, S.A. (ES) 2003-01-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040147545-A1 Derivatives of oxazolidinones as antibacterial agents OXA1L, Q6ZSR9, PGC F10 1608/4885MAOB 711/4885MAOA 697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.