Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESRRA | P11474 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 5/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | PDE6D | O43924 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21636079 | 0.93 | MAPK1 (0.46) | PDE10AMAPK1KMT2AESR1ESRRA | |
| SCHEMBL21636112 | 0.92 | MAPK1 (0.41) | PDE10AMAPK1KMT2AESR1ESRRA | |
| SCHEMBL21636025 | 0.90 | MAPK1 (0.44) | PDE10AMAPK1KMT2AESR1ESRRA | |
| SCHEMBL26042560 | 0.90 | MAPK1 (0.46) | MAPK1KMT2AESR1ESRRAESR2 | |
| SCHEMBL21636086 | 0.90 | MAPK1 (0.46) | MAPK1KMT2AESR1ESRRAESR2 | |
| SCHEMBL21636026 | 0.90 | MAPK1 (0.46) | MAPK1KMT2AESR1ESRRAESR2 | |
| SCHEMBL20227635 | 0.90 | MAPK1 (0.46) | MAPK1KMT2AESR1ESRRAESR2 | |
| SCHEMBL21636107 | 0.89 | MAPK1 (0.45) | PDE10AMAPK1KMT2AESR1ESRRA | |
| SCHEMBL21636052 | 0.88 | MAPK1 (0.49) | PDE10AMAPK1KMT2ANPSR1L3MBTL1 | |
| SCHEMBL23156551 | 0.87 | L3MBTL1 (0.44) | PDE10AKMT2AMAPK14L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3823958-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2023-08-23 | — | — | EP | disclosed |
| WO-2020016264-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-01-23 | — | — | WO | disclosed |