SCHEMBL216366

SCHEMBL216366

O=C(C(Br)Br)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26089487 1.00 ALDH1A1 (0.39)
Water SCHEMBL21725015 0.97 ALDH1A1 (0.37)
SCHEMBL6906960 0.78
SCHEMBL5860801 0.78
SCHEMBL15293930 0.75 THRB (0.35)
SCHEMBL4758128 0.75
SCHEMBL11635042 0.75
SCHEMBL1135458 0.75
SCHEMBL2650133 0.75
SCHEMBL28130620 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 997 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113861194-B Pyrrolopyridine-containing bisamide imidazole compound and preparation method and application thereof 英维沃化工科技(广州)有限公司 2022-07-05 CN claimed
CN-113861194-A Pyrrolopyridine-containing bisamide imidazole compound and preparation method and application thereof 英维沃化工科技(广州)有限公司 2021-12-31 CN claimed
US-20210332040-A1 SUBSTITUTED 4-AMINO-1H-IMIDAZO[4,5-c]QUINOLINE COMPOUNDS AND IMPROVED METHODS FOR THEIR PREPARATION INNATE TUMOR IMMUNITY INC (US) 2021-10-28 US claimed
CN-106187904-B Propiolamido-containing 2-phenylimidazole derivative and preparation method, pharmaceutical composition and application thereof 中国医学科学院药物研究所 2021-07-06 CN claimed
EP-3837245-A1 SUBSTITUED 4-AMINO-1H-IMIDAZO[4,5-C]QUINOLINE COMPOUNDS AND IMPROVED METHODS FOR THEIR PREPARATION Innate Tumor Immunity, Inc. (US) 2021-06-23 EP claimed
CN-112888677-A Substituted 4-amino-1H-imidazo [4,5-c ] quinoline compounds and improved process for their preparation 先天肿瘤免疫公司 2021-06-01 CN claimed
WO-2020037094-A1 SUBSTITUED 4-AMINO-1H-IMIDAZO[4,5-C]QUINOLINE COMPOUNDS AND IMPROVED METHODS FOR THEIR PREPARATION INNATE TUMOR IMMUNITY, INC. (US) 2020-02-20 WO claimed
US-4125530-A FROM 1,1-DIHALO-3,3,3-TRIFLUOROACETONE, BASE, AMMONIA AND A CARBOXALDEHYDE MERCK & CO., INC. (US) 1978-11-14 US claimed
JP-10316676-A None JP disclosed
WO-2026107227-A1 COMPOSITIONS COMPRISING USP1 INHIBITORS AND METHODS OF USING THE SAME EIKON THERAPEUTICS, INC. (US) 2026-05-21 WO disclosed
EP-4741386-A1 PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF Jiangsu Yahong Meditech Co., Ltd. (CN) 2026-05-13 EP disclosed
EP-4739397-A1 FUSED PYRAZOLE DERIVATIVES AS USP1 INHIBITORS Exelixis, Inc. (US) 2026-05-13 EP disclosed
US-20260125378-A2 Heterocyclic Compounds BEONE MEDICINES I GMBH (CH) 2026-05-07 US disclosed
US-20260125360-A1 HERBICIDAL IMIDAZOLE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2026-05-07 US disclosed
US-4293552-A Novel 1-(mono-o-substituted benzoyl)-3-(substituted pyrazinyl) ureas ELI LILLY AND COMPANY (US) 1981-10-06 US disclosed
US-4199580-A HYPOTENSIVE AGENTS AND ADRENERGIC BLOCKING AGENTS MERCK & CO., INC. (US) 1980-04-22 US disclosed
US-4160834-A INSECTICIDES ELI LILLY AND COMPANY (US) 1979-07-10 US disclosed
US-4134983-A HYPOTENSIVE, ADRENERGIC BLOCKING AGENTS MERCK & CO., INC. (US) 1979-01-16 US disclosed
US-4125530-A FROM 1,1-DIHALO-3,3,3-TRIFLUOROACETONE, BASE, AMMONIA AND A CARBOXALDEHYDE MERCK & CO., INC. (US) 1978-11-14 US disclosed
US-4032522-A ANTI-GOUT, ANTI-HYPERURICEMIC MERCK & CO., INC. (US) 1977-06-28 US disclosed