Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | ALB | P02768 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | TYMP | P19971 | 2/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.43 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | GSK3A | P49840 | 2/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21540015 | 0.86 | ALDH1A1 (0.73) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL21393026 | 0.85 | ALDH1A1 (0.50) | ALDH1A1LMNAALBMAPK1STING1 | |
| SCHEMBL21637037 | 0.84 | ALDH1A1 (0.78) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL24358288 | 0.83 | ALDH1A1 (0.80) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL13773372 | 0.83 | BCHE (0.54) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| SCHEMBL12395247 | 0.82 | ALDH1A1 (0.71) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL21637018 | 0.82 | ALDH1A1 (0.71) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL21417219 | 0.82 | ALDH1A1 (0.71) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL14884635 | 0.82 | ALDH1A1 (0.71) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL20327576 | 0.82 | ALDH1A1 (0.71) | ALDH1A1LMNAALBMAPK1TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020016782-A1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | JANSSEN BIOTECH, INC. (US) | 2020-01-23 | — | — | WO | disclosed |