Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HINT1 | P49773 | 4/20 | 0.47 |
| ▸ | PNP | P00491 | 2/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | KRAS | P01116 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 2/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22402617 | 0.88 | ALDH1A1 (0.52) | ALDH1A1LMNAALBMAPK1POLB | |
| SCHEMBL18763358 | 0.88 | ALDH1A1 (0.52) | ALDH1A1LMNAALBMAPK1POLB | |
| SCHEMBL22523989 | 0.88 | ALDH1A1 (0.52) | ALDH1A1LMNAALBMAPK1POLB | |
| SCHEMBL26794936 | 0.88 | ALDH1A1 (0.52) | ALDH1A1LMNAALBMAPK1POLB | |
| SCHEMBL18520392 | 0.88 | ALDH1A1 (0.52) | ALDH1A1LMNAALBMAPK1POLB | |
| SCHEMBL25057493 | 0.88 | ALDH1A1 (0.52) | ALDH1A1LMNAALBMAPK1POLB | |
| SCHEMBL16144132 | 0.87 | ALDH1A1 (0.51) | ALDH1A1LMNAALBMAPK1POLB | |
| SCHEMBL26196385 | 0.86 | ALDH1A1 (0.55) | ALDH1A1LMNAALBMAPK1POLB | |
| SCHEMBL21636979 | 0.85 | ALDH1A1 (0.69) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| SCHEMBL23516965 | 0.85 | ALDH1A1 (0.49) | ALDH1A1LMNAALBMAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210015915-A1 | STING MODULATOR COMPOUNDS WITH SULFAMATE LINKAGES, AND METHODS OF MAKING AND USING | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-01-21 | — | — | US | disclosed |
| WO-2019180683-A1 | STING MODULATOR COMPOUNDS WITH SULFAMATE LINKAGES, AND METHODS OF MAKING AND USING | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-09-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210015915-A1 | STING MODULATOR COMPOUNDS WITH SULFAMATE LINKAGES, AND METHODS OF MAKING AND USING | STING1, CGAS, TBK1 | ALDH1A1 4387/4885LMNA 3449/4885ALB 4880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.