Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | IMPDH2 | P12268 | 6/20 | 0.54 |
| ▸ | TGM2 | P21980 | 1/20 | 0.53 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.52 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.51 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.51 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.50 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.49 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.49 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.49 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.49 |
| ▸ | PNP | P00491 | 1/20 | 0.48 |
| ▸ | KRAS | P01116 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21636997 | 1.00 | NT5E (0.56) | NT5EPOLBIMPDH2TGM2TAS1R3 | |
| SCHEMBL21417496 | 1.00 | NT5E (0.56) | NT5EPOLBIMPDH2TGM2TAS1R3 | |
| SCHEMBL20442307 | 0.90 | POLB (0.61) | NT5EPOLBIMPDH2TGM2TAS1R3 | |
| SCHEMBL2922052 | 0.90 | POLB (0.61) | NT5EPOLBIMPDH2TGM2TAS1R3 | |
| SCHEMBL20698981 | 0.90 | NT5E (0.57) | NT5EPOLBIMPDH2TGM2TAS1R3 | |
| SCHEMBL21132941 | 0.87 | POLB (0.67) | NT5EPOLBIMPDH2TGM2TAS1R3 | |
| SCHEMBL20324606 | 0.87 | POLB (0.67) | NT5EPOLBIMPDH2TGM2TAS1R3 | |
| SCHEMBL9856344 | 0.87 | POLB (0.67) | NT5EPOLBIMPDH2TGM2TAS1R3 | |
| SCHEMBL23760838 | 0.86 | NT5E (0.54) | NT5EPOLBIMPDH2TGM2TAS1R3 | |
| SCHEMBL6053623 | 0.86 | STING1 (0.52) | NT5ESTING1HPRT1PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020016782-A1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | JANSSEN BIOTECH, INC. (US) | 2020-01-23 | — | — | WO | disclosed |