Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TGM2 | P21980 | 1/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.50 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.49 |
| ▸ | IMPDH2 | P12268 | 6/20 | 0.49 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.49 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.47 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.47 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.47 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.47 |
| ▸ | KRAS | P01116 | 3/20 | 0.46 |
| ▸ | HINT1 | P49773 | 1/20 | 0.46 |
| ▸ | PNP | P00491 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24081863 | 0.92 | FUT5 (0.55) | NT5EPOLBTGM2FUT5P2RY2 | |
| SCHEMBL20442307 | 0.87 | POLB (0.61) | NT5EPOLBTGM2TAS1R3TAS1R1 | |
| SCHEMBL20698981 | 0.87 | NT5E (0.57) | NT5EPOLBTGM2TAS1R3TAS1R1 | |
| SCHEMBL2922052 | 0.87 | POLB (0.61) | NT5EPOLBTGM2TAS1R3TAS1R1 | |
| SCHEMBL12966940 | 0.87 | HPGD (0.48) | NT5EHPRT1HINT1 | |
| SCHEMBL21636997 | 0.86 | NT5E (0.56) | NT5EPOLBTGM2TAS1R3TAS1R1 | |
| SCHEMBL21417496 | 0.86 | NT5E (0.56) | NT5EPOLBTGM2TAS1R3TAS1R1 | |
| SCHEMBL21636981 | 0.86 | NT5E (0.56) | NT5EPOLBTGM2TAS1R3TAS1R1 | |
| SCHEMBL24081859 | 0.84 | PNP (0.51) | POLBHPRT1PNP | |
| SCHEMBL18158915 | 0.82 | NT5E (0.53) | NT5EPOLBTGM2TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3865136-A1 | 2'-SUBSTITUTED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR CORONA VIRUS TREATMENT | ATEA Pharmaceuticals, Inc. (US) | 2021-08-18 | — | — | EP | disclosed |