Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | ARG2 | P78540 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13373175 | 1.00 | MAOB (0.61) | MAOBCA1CA2ARG2KDM4E | |
| SCHEMBL13373247 | 0.85 | MAOB (0.54) | MAOBCA1CA2ARG2KDM4E | |
| SCHEMBL21747039 | 0.80 | AGXT (0.40) | MAOBKDM4EMAPTTAAR1MAPK1 | |
| SCHEMBL4430706 | 0.77 | MAOB (0.68) | MAOBCA1CA2ARG2KDM4E | |
| SCHEMBL9416674 | 0.77 | MAOB (0.61) | MAOBCA1CA2ARG2CYP3A4 | |
| SCHEMBL28018372 | 0.77 | MAOB (0.61) | MAOBCA1CA2ARG2CYP3A4 | |
| SCHEMBL155055 | 0.77 | MAOB (1.00) | MAOBCA1CA2ARG2CALM1 | |
| SCHEMBL155054 | 0.77 | MAOB (1.00) | MAOBCA1CA2ARG2CALM1 | |
| SCHEMBL1524697 | 0.77 | MAOB (1.00) | MAOBCA1CA2ARG2CALM1 | |
| SCHEMBL6014376 | 0.77 | MAOB (0.54) | MAOBCA1CA2ARG2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020018779-A1 | USE OF PHENYLETHYLIDENEHYDRAZINE TO TREAT SEIZURE DISORDERS, DEVELOPMENTAL DISORDERS, NEUROLOGICAL DISORDERS, BEHAVIORAL DISORDERS AND ADDICTION | OVID THERAPEUTICS INC. (US) | 2020-01-23 | — | — | WO | disclosed |