SCHEMBL21638239

SCHEMBL21638239

COCCOC1CCN(c2ccc(C(=O)O)cc2)C1

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 7/20 0.53
LIPC P11150 2/20 0.53
USP2 O75604 1/20 0.52
ACACB O00763 2/20 0.47
FFAR4 Q5NUL3 3/20 0.42
HRH1 P35367 1/20 0.42
CCR3 P51677 1/20 0.42
KCNH2 Q12809 1/20 0.42
CASR P41180 3/20 0.41
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21669125 1.00 LIPG (0.53) LIPGLIPCUSP2ACACBFFAR4
SCHEMBL21638237 1.00 LIPG (0.53) LIPGLIPCUSP2ACACBFFAR4
SCHEMBL21669102 0.85 LIPG (0.47) LIPGLIPCACACB
SCHEMBL23839397 0.85 LIPG (0.47) LIPGLIPCACACB
SCHEMBL21669124 0.85 LIPG (0.47) LIPGLIPCACACB
SCHEMBL4578782 0.84 USP2 (0.60) USP2ACACBFFAR4HRH1CCR3
SCHEMBL20046768 0.84 USP2 (0.60) USP2ACACBFFAR4HRH1CCR3
SCHEMBL8228558 0.84 USP2 (0.60) USP2ACACBFFAR4HRH1CCR3
SCHEMBL19297613 0.81 LIPG (0.46) LIPGLIPCACACBFFAR4KDM4E
SCHEMBL24213939 0.81 LIPG (0.60) LIPGLIPCACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110475775-B 4-pyridone compound or salt thereof, pharmaceutical composition containing 4-pyridone compound, and agent 富士胶片株式会社 2023-05-09 CN disclosed
US-11161830-B2 4-pyridone compound or salt thereof, and pharmaceutical composition and formulation including same FUJIFILM CORPORATION (JP) 2021-11-02 US disclosed
EP-3604301-B1 4-PYRIDONE COMPOUND OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION AND FORMULATION INCLUDING SAME FUJIFILM CORP (JP) 2021-09-22 EP disclosed
EP-3604301-A1 4-PYRIDONE COMPOUND OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION AND FORMULATION INCLUDING SAME FUJIFILM Corporation (JP) 2020-02-05 EP disclosed
EP-3604301-A1 4-PYRIDONE COMPOUND OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION AND FORMULATION INCLUDING SAME FUJIFILM Corporation (JP) 2020-02-05 EP disclosed
CN-110475775-A 4- pyridinone compounds or its salt, pharmaceutical composition and agent comprising 4- pyridinone compounds FUJIFILM CORP 2019-11-19 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11161830-B2 4-pyridone compound or salt thereof, and pharmaceutical composition and formulation including same HAVCR2, HBS1L, PHKB LIPG 4820/4885LIPC 3754/4885USP2 4880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.