Itaconate

Itaconate

SCHEMBL216384

C=C(CC(=O)O)C(=O)O.OCCO.OCCO

nearest known ligand 0.83

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.65
HSD17B10 Q99714 1/20 0.65
LDHA P00338 1/20 0.42
SRR Q9GZT4 1/20 0.42
TET2 Q6N021 5/20 0.37
TET3 O43151 1/20 0.37
TET1 Q8NFU7 1/20 0.37
FNTA P49354 1/20 0.37
FNTB P49356 1/20 0.37
GRIK1 P39086 1/20 0.36
GRIK2 Q13002 1/20 0.36
GRM1 Q13255 1/20 0.36
GRM2 Q14416 1/20 0.36
KDM4E B2RXH2 1/20 0.33
TSHR P16473 1/20 0.33
CAMK2A Q9UQM7 1/20 0.33
GPR84 Q9NQS5 1/20 0.31
FFAR1 O14842 1/20 0.31
FFAR4 Q5NUL3 1/20 0.31
OR51E2 Q9H255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Itaconate SCHEMBL27940416 1.00 ALOX15 (0.65) ALOX15HSD17B10LDHASRRTET2
Itaconate SCHEMBL304510 1.00 ALOX15 (0.65) ALOX15HSD17B10LDHASRRTET2
Itaconate SCHEMBL10967892 0.97 ALOX15 (0.62) ALOX15HSD17B10LDHASRRTET2
Itaconate SCHEMBL29886131 0.91
Itaconate SCHEMBL21523 0.91
Itaconate SCHEMBL286967 0.91 ALOX15 (0.75) ALOX15HSD17B10LDHASRRTET2
Itaconate SCHEMBL9068843 0.91 ALOX15 (0.56) ALOX15HSD17B10LDHASRRTET2
Itaconate SCHEMBL27319934 0.91 ALOX15 (0.56) ALOX15HSD17B10LDHASRRTET2
Itaconate SCHEMBL21043626 0.90 ALOX15 (0.60) ALOX15HSD17B10LDHASRRTET2
Itaconate SCHEMBL9328495 0.90 ALOX15 (0.60) ALOX15HSD17B10LDHASRRTET2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101372526-B High activity catalyst for synthesizing polycarboxylic acid dehydragent and use thereof AIQUN DONG 2010-08-18 CN claimed
US-6111045-A YIELDS A VULCANIZED RUBBER SHOWING IMPROVEMENTS IN HEAT BUILD-UP, TENSILE STRENGTH, ABRASION RESISTANCE AND PROCESSABILITY NIPPON ZEON CO. LTD. (JP) 2000-08-29 US claimed
US-4950711-A CONJUGATED DIENE, MONOOLEFIN, AND UNSATURATED CARBOXYLIC ACID MONOMERS REICHHOLD CHEMICALS, INC. (US) 1990-08-21 US claimed
US-3941912-A Copolymer latex and paper coating composition thereof SUMITOMO NAUGATUCK CO., LTD. (JA) 1976-03-02 US claimed
JP-59053835-A None JP disclosed
WO-2024106435-A1 AQUEOUS LUMINOUS PIGMENT COMPOSITION 日本エイアンドエル株式会社 2024-05-23 WO disclosed
WO-2024048587-A1 COPOLYMER LATEX FOR CARBON DIOXIDE SEPARATOR, COMPOSITION FOR CARBON DIOXIDE SEPARATOR, CARBON DIOXIDE SEPARATOR, AND METHOD FOR PREPARING CARBON DIOXIDE SEPARATOR 日本エイアンドエル株式会社 2024-03-07 WO disclosed
WO-2023167259-A1 METHOD FOR PRODUCING LAMINATION MOLDED ARTICLE, HEAT-SENSITIVE GELLING AGENT, AND LAMINATION MOLDING COMPOSITION 日本エイアンドエル株式会社 2023-09-07 WO disclosed
EP-3396748-B1 BINDER COMPOSITION FOR NON-AQUEOUS SECONDARY BATTERY ELECTRODE, SLURRY COMPOSITION FOR NON-AQUEOUS SECONDARY BATTERY ELECTRODE, ELECTRODE FOR NON-AQUEOUS SECONDARY BATTERY, AND NON-AQUEOUS SECONDARY BATTERY ZEON CORP (JP) 2023-05-03 EP disclosed
CN-110710035-B Binder composition for electrochemical element electrode, electrode for electrochemical element, and electrochemical element 日本瑞翁株式会社 2023-04-28 CN disclosed
US-11552297-B2 Binder composition for lithium ion secondary battery electrode-use, slurry composition for lithium ion secondary battery electrode-use, electrode for lithium ion secondary battery-use, and lithium ion secondary battery ZEON CORPORATION (JP) 2023-01-10 US disclosed
WO-2023277034-A1 COPOLYMER EMULSION, THERMOPLASTIC RESIN EMULSION, COMPOSITION FOR FIBER BINDING, RESIN-IMPREGNATED FIBER USING SAME, THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE 日本エイアンドエル株式会社 2023-01-05 WO disclosed
EP-0591556-A1 METHOD OF PRODUCING POLYMERIC LATEX SUMITOMO DOW LIMITED (JP) 1994-04-13 EP disclosed
EP-0575625-A1 PROCESS FOR PRODUCING COPOLYMER LATEX AND USE THEREOF SUMITOMO DOW LIMITED (JP) 1993-12-29 EP disclosed
US-4950711-A CONJUGATED DIENE, MONOOLEFIN, AND UNSATURATED CARBOXYLIC ACID MONOMERS REICHHOLD CHEMICALS, INC. (US) 1990-08-21 US disclosed
JP-S5953835-A WATER-SOLUBLE PHOTOHARDENABLE RESIN COMPOSITION NIPPON OIL & FATS CO LTD 1984-03-28 JP disclosed
US-4429074-A CARBON TETRACHLORIDE AND A MERCAPTAN AS CHAIN TRANSFER AGENT SUMITOMO NAUGATUCK CO., LTD. (JP) 1984-01-31 US disclosed
US-4381365-A Copolymer latex and its production SUMITOMO NAUGATUCK CO., LTD. (JP) 1983-04-26 US disclosed
EP-0013031-A1 A paper coating composition and its production Sumitomo Naugatuck Co., Ltd. (JP) 1980-07-09 EP disclosed
US-3941912-A Copolymer latex and paper coating composition thereof SUMITOMO NAUGATUCK CO., LTD. (JA) 1976-03-02 US disclosed