Itaconate

Itaconate

SCHEMBL9328495

C=C(CC(=O)O)C(=O)O.C=C(CC(=O)O)C(=O)O.OCCCCO

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.60
HSD17B10 Q99714 1/20 0.60
FNTA P49354 1/20 0.48
FNTB P49356 1/20 0.48
GPR84 Q9NQS5 1/20 0.44
FFAR1 O14842 1/20 0.44
FFAR4 Q5NUL3 1/20 0.44
CAMK2A Q9UQM7 1/20 0.42
LDHA P00338 1/20 0.38
SRR Q9GZT4 1/20 0.38
TET2 Q6N021 5/20 0.34
TET3 O43151 1/20 0.34
TET1 Q8NFU7 1/20 0.34
GRIK1 P39086 1/20 0.33
GRIK2 Q13002 1/20 0.33
GRM1 Q13255 1/20 0.33
GRM2 Q14416 1/20 0.33
KDM4E B2RXH2 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Itaconate SCHEMBL5091755 1.00 ALOX15 (0.60) ALOX15HSD17B10FNTAFNTBGPR84
Itaconate SCHEMBL10524435 0.98 HSD17B10 (0.58) ALOX15HSD17B10FNTAFNTBGPR84
Itaconate SCHEMBL21043626 0.95 ALOX15 (0.60) ALOX15HSD17B10FNTAFNTBGPR84
Itaconate SCHEMBL216384 0.90 ALOX15 (0.65) ALOX15HSD17B10FNTAFNTBGPR84
Itaconate SCHEMBL304510 0.90 ALOX15 (0.65) ALOX15HSD17B10FNTAFNTBGPR84
Itaconate SCHEMBL27940416 0.90 ALOX15 (0.65) ALOX15HSD17B10FNTAFNTBGPR84
Docosanol SCHEMBL29145466 0.88 TSHR (0.50) ALOX15HSD17B10FNTAFNTBGPR84
Cetostearyl Alcohol SCHEMBL28383243 0.88 TSHR (0.50) ALOX15HSD17B10FNTAFNTBGPR84
Dodecanol SCHEMBL29188659 0.88 TSHR (0.50) ALOX15HSD17B10FNTAFNTBGPR84
Cetyl Alcohol SCHEMBL27838346 0.88 TSHR (0.50) ALOX15HSD17B10FNTAFNTBGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250263566-A1 CASTING LACQUER FOR SCREEN PRINTING DE LA RUE INTERNATIONAL LIMITED (GB) 2025-08-21 US claimed
EP-4490577-A1 CASTING LACQUER FOR SCREEN PRINTING BASF SE (DE) 2025-01-15 EP claimed
WO-2023170132-A1 CASTING LACQUER FOR SCREEN PRINTING BASF SE (DE) 2023-09-14 WO claimed
EP-0399755-B1 Light-sensitive composition and presensitized plate for use in making lithographic printing plates FUJI PHOTO FILM CO LTD (JP) 1994-03-30 EP claimed
EP-4743828-A1 PHOTOCURABLE AS WELL AS THERMALLY CURABLE COMPOSITIONS SUITABLE FOR LOW TEMPERATURE CURING BASF SE (DE) 2026-05-20 EP disclosed
WO-2026099089-A1 PATTERN-CONTROLLED SURFACE RELIEF STRUCTURES COMPRISING LIQUID CRYSTALS BASF SE (DE) 2026-05-15 WO disclosed
US-20260132298-A1 A METHOD FOR PRODUCING INTERFERENCE ELEMENTS BASF SE (DE) 2026-05-14 US disclosed
EP-4555021-B1 UV-CURABLE COATINGS HAVING HIGH REFRACTIVE INDEX BASF SE (DE) 2026-05-13 EP disclosed
EP-4347710-B1 MIXER SYSTEM FOR PRODUCING AQUEOUS COATING MATERIALS BASF COATINGS GMBH (DE) 2026-05-13 EP disclosed
EP-4709544-A1 COMPOSITIONS, COMPRISING SILVER NANOPLATELETS BASF SE (DE) 2026-03-18 EP disclosed
EP-4702061-A1 COMPOSITIONS, USES AND METHODS Innospec Limited (GB) 2026-03-04 EP disclosed
US-20260008936-A1 UV-CURABLE COATINGS HAVING HIGH REFRACTIVE INDEX BASF SE (DE) 2026-01-08 US disclosed
US-20220121113-A1 OXIME ESTER PHOTOINITIATORS HAVING A SPECIAL AROYL CHROMOPHORE BASF SE (DE) 2022-04-21 US disclosed
US-20220097437-A1 SECURITY ELEMENT BASF SE (DE) 2022-03-31 US disclosed
US-20220088957-A1 SECURITY ELEMENT BASF SE (DE) 2022-03-24 US disclosed
EP-3965983-A1 COMPOSITIONS, COMPRISING SILVER NANOPLATELETS BASF SE (DE) 2022-03-16 EP disclosed
US-11274219-B2 Surface functionalized titanium dioxide nanoparticles BASF SE (DE) 2022-03-15 US disclosed
WO-2022038161-A1 UV-CURABLE COATINGS HAVING HIGH REFRACTIVE INDEX BASF SE (DE) 2022-02-24 WO disclosed
US-11256028-B2 Thermally resistant radiation curable coatings for optical fiber COVESTRO (NETHERLANDS) B.V. (NL) 2022-02-22 US disclosed
EP-3941970-A1 UV CURABLE COMPOSITIONS FOR DIRT PICK-UP RESISTANCE BASF SE (DE) 2022-01-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132298-A1 A METHOD FOR PRODUCING INTERFERENCE ELEMENTS COPE, COPB2, C9 ALOX15 4306/4885HSD17B10 3644/4885FNTA 2933/4885
US-20260008936-A1 UV-CURABLE COATINGS HAVING HIGH REFRACTIVE INDEX B2M, MGMT, ITGAM ALOX15 305/4885HSD17B10 4284/4885FNTA 2961/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.