Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 9/20 | 0.46 |
| ▸ | CCNC | P24863 | 4/20 | 0.39 |
| ▸ | CDK8 | P49336 | 4/20 | 0.39 |
| ▸ | PAICS | P22234 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 2/20 | 0.36 |
| ▸ | KHK | P50053 | 3/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16722296 | 0.90 | BRD4 (0.53) | BRD4CCNCCDK8PAICSKHK | |
| SCHEMBL16721827 | 0.89 | BRD4 (0.45) | BRD4CCNCCDK8PAICSEP300 | |
| SCHEMBL21638695 | 0.88 | BRD4 (0.47) | BRD4CCNCCDK8EP300NAMPT | |
| SCHEMBL21638678 | 0.87 | BRD4 (0.48) | BRD4NAMPT | |
| SCHEMBL16721804 | 0.87 | BRD4 (0.52) | BRD4CCNCCDK8PAICSKHK | |
| SCHEMBL21638519 | 0.86 | BRD4 (0.46) | BRD4PAICSKHKNAMPT | |
| SCHEMBL21638456 | 0.86 | BRD4 (0.49) | BRD4NAMPT | |
| SCHEMBL16721936 | 0.85 | BRD4 (0.51) | BRD4CCNCCDK8PAICSKHK | |
| SCHEMBL21638680 | 0.85 | BRD4 (0.48) | BRD4NAMPT | |
| SCHEMBL21638444 | 0.84 | BRD4 (0.47) | BRD4CCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3071205-B1 | BENZOPIPERAZINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS | FORMA THERAPEUTICS INC (US) | 2020-02-05 | — | — | EP | disclosed |