SCHEMBL2164002

SCHEMBL2164002

NNS(=O)(=O)c1ccc(Cl)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.61
CA2 P00918 3/20 0.61
CA12 O43570 2/20 0.61
CA3 P07451 2/20 0.61
CA4 P22748 2/20 0.61
CA6 P23280 2/20 0.61
CA5A P35218 2/20 0.61
CA7 P43166 2/20 0.61
CA9 Q16790 2/20 0.61
CA13 Q8N1Q1 2/20 0.61
CA14 Q9ULX7 2/20 0.61
CA5B Q9Y2D0 2/20 0.61
MMP1 P03956 1/20 0.61
MMP2 P08253 1/20 0.61
MMP9 P14780 1/20 0.61
MMP8 P22894 1/20 0.61
MMP13 P45452 1/20 0.61
CES1 P23141 1/20 0.59
F2 P00734 1/20 0.55
PRSS1 P07477 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30724549 1.00 CA1 (0.61) CA1CA2CA12CA3CA4
SCHEMBL1706125 0.87 SMN1; SMN2 (0.59) CA1CA2CA12CA3CA4
SCHEMBL6926687 0.80 CA2 (0.67) CA1CA2CA12CA3CA4
SCHEMBL3065124 0.80 ALDH1A1 (0.53) CA1CA2CA12CA9CA14
SCHEMBL12353348 0.78 CA2 (0.64) CA1CA2CA12CA3CA4
SCHEMBL6241936 0.78 CA1 (0.64) CA1CA2CA12CA4CA6
SCHEMBL2442745 0.76 CA1 (1.00) CA1CA2CA12CA3CA4
SCHEMBL10531775 0.76 CA2 (0.61) CA1CA2CA12CA3CA4
SCHEMBL8779439 0.76 CA2 (0.61) CA1CA2CA12CA3CA4
SCHEMBL334232 0.76 CA1 (0.61) CA1CA2CA9MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117535689-A Method for synthesizing sulfonamide through decarbonylation of N, N-dimethylformamide and denitrification of sulfonyl hydrazide under electrochemical condition 湘潭大学 2024-02-09 CN claimed
CN-116162046-A Alkynyl sulfone derivative and preparation method and application thereof 云南民族大学 2023-05-26 CN claimed
EP-3670490-B1 METHOD OF PURIFYING PINE CHEMICAL COMPOSITIONS FROM ALDEHYDES KRATON POLYMERS LLC (US) 2023-01-18 EP claimed
CN-112409236-B Method for synthesizing 3-thioether indole with high selectivity 上海应用技术大学 2022-10-14 CN claimed
CN-114318377-A Method for catalyzing olefin fluorosulfonation through electrochemistry 南京林业大学 2022-04-12 CN claimed
CN-111689883-B Synthetic method of diaryl sulfone compound 上海应用技术大学 2022-02-11 CN claimed
CN-112409236-A Method for synthesizing 3-thioether indole with high selectivity 上海应用技术大学 2021-02-26 CN claimed
CN-111689883-A Synthetic method of diaryl sulfone compound 上海应用技术大学 2020-09-22 CN claimed
EP-3670490-A1 METHOD OF PURIFYING PINE CHEMICAL COMPOSITIONS FROM ALDEHYDES Kraton Polymers LLC (US) 2020-06-24 EP claimed
US-20200165191-A1 Method of Purifying Pine Chemical Compositions from Aldehydes KRATON POLYMERS LLC (US) 2020-05-28 US claimed
CN-110698368-A Preparation method of (E) -3-phenyl-3-benzenesulfonyl acrylate compound 湖南大学 2020-01-17 CN claimed
US-5527920-A Economical manufacturing process for 1,2,3-triazoles SYNPHAR LABORATORIES, INC. (CA) 1996-06-18 US claimed
WO-1996004255-A1 PRODUCTION OF 1,2,3-TRIAZOLES BY CYCLOCONDENSATION OF HYDRAZIDES WITH GLYOXAL AND AMINES SYNPHAR LABORATORIES, INC. (US) 1996-02-15 WO claimed
US-5478947-A Effective process for the production of 1,2,3-triazoles SYNPHAR LABORATORIES, INC. (CA) 1995-12-26 US claimed
JP-7278121-A None JP disclosed
CN-116162046-B Alkynyl sulfone derivative and preparation method and application thereof 云南民族大学 2025-06-13 CN disclosed
CN-119569658-A Sulfonyl pyridazinone compound and preparation method and application thereof 华南师范大学 2025-03-07 CN disclosed
US-4133832-A Blowing agents -bis(hydrocarbylsulfonyl) carbohydrazides UNIROYAL, INC. (US) 1979-01-09 US disclosed
US-4096100-A Blowing agents-bis(hydrocarbylsulfonyl) carbohydrazides UNIROYAL, INC. (US) 1978-06-20 US disclosed
US-3987019-A ACRYLIC ESTER, PEROXIDE POLYMERIZATION CATALYST HENKEL & CIE G.M.B.H. (DT) 1976-10-19 US disclosed