SCHEMBL21643014

SCHEMBL21643014

N#Cc1csc(-c2coc(-c3csc(CC(N)C(=O)O)n3)n2)n1

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.31
GRIA1 P42261 1/20 0.31
GRIA2 P42262 1/20 0.31
GRIA3 P42263 1/20 0.31
GRIA4 P48058 1/20 0.31
GRIK2 Q13002 1/20 0.31
GRIK3 Q13003 1/20 0.31
GRIK4 Q16099 1/20 0.31
GRIK5 Q16478 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21643011 1.00 GRIK1 (0.31) GRIK1GRIA1GRIA2GRIA3GRIA4
SCHEMBL21643061 0.93 DPP4 (0.31) GRIK1GRIA1GRIA2GRIA3GRIA4
SCHEMBL21643053 0.88 USP2 (0.33) GRIK1GRIA1GRIA2GRIA3GRIA4
SCHEMBL21643038 0.87 CES1 (0.32) GRIA2
SCHEMBL21643039 0.87 CES1 (0.32) GRIA2
SCHEMBL21643032 0.87 USP2 (0.33) GRIK1GRIA1GRIA2GRIA3GRIA4
SCHEMBL21643010 0.87 USP2 (0.33) GRIK1GRIA1GRIA2GRIA3GRIA4
SCHEMBL21642993 0.81 EIF4E (0.34)
SCHEMBL21642995 0.81 EIF4E (0.34)
SCHEMBL21643047 0.81 GABRA5 (0.31) GRIA1GRIA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11319347-B2 Peptide compound and method for producing same, composition for screening use, and method for selecting peptide compound FUJIFILM CORPORATION (JP) 2022-05-03 US disclosed
US-20200040039-A1 PEPTIDE COMPOUND AND METHOD FOR PRODUCING SAME, COMPOSITION FOR SCREENING USE, AND METHOD FOR SELECTING PEPTIDE COMPOUND FUJIFILM CORPORATION (JP) 2020-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200040039-A1 PEPTIDE COMPOUND AND METHOD FOR PRODUCING SAME, COMPOSITION FOR SCREENING USE, AND METHOD FOR SELECTING PEPTIDE COMPOUND VIP, NPPA, NGLY1 GRIK1 1321/4885GRIA1 2562/4885GRIA2 3146/4885
US-11319347-B2 Peptide compound and method for producing same, composition for screening use, and method for selecting peptide compound VIP, NPPA, NGLY1 GRIK1 1321/4885GRIA1 2562/4885GRIA2 3146/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.