Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | APP | P05067 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA3 | P07451 | 2/20 | 0.57 |
| ▸ | CA4 | P22748 | 2/20 | 0.57 |
| ▸ | CA6 | P23280 | 2/20 | 0.57 |
| ▸ | CA5A | P35218 | 2/20 | 0.57 |
| ▸ | CA7 | P43166 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28226138 | 1.00 | PTPN1 (1.00) | PTPN1MAPTAPPMEN1CYP3A4 | |
| SCHEMBL14966981 | 1.00 | PTPN1 (1.00) | PTPN1MAPTAPPMEN1CYP3A4 | |
| SCHEMBL30983773 | 1.00 | PTPN1 (1.00) | PTPN1MAPTAPPMEN1CYP3A4 | |
| SCHEMBL27677458 | 0.86 | PTPN1 (0.76) | PTPN1MAPTMEN1CYP3A4KMT2A | |
| SCHEMBL23883121 | 0.81 | PTPN1 (0.68) | PTPN1MAPTAPPMEN1CYP3A4 | |
| SCHEMBL30739556 | 0.81 | PTPN1 (0.68) | PTPN1MAPTAPPMEN1CYP3A4 | |
| SCHEMBL13313586 | 0.81 | PTPN1 (0.68) | PTPN1MAPTAPPMEN1CYP3A4 | |
| SCHEMBL29126777 | 0.81 | PTPN1 (0.68) | PTPN1MAPTAPPMEN1CYP3A4 | |
| SCHEMBL31414593 | 0.81 | PTPN1 (0.68) | PTPN1MAPTAPPMEN1CYP3A4 | |
| SCHEMBL31414592 | 0.81 | PTPN1 (0.68) | PTPN1MAPTAPPMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109991340-B | Spectrum effect relationship-based quality detection method for radix polygoni multiflori preparata | 无限极（中国）有限公司 | 2022-03-29 | — | — | CN | disclosed |
| US-20210038535-A1 | PHARMACEUTICAL COMPOUND FOR TREATING COLORECTAL CANCER | LIAO SE CHUN (TW) | 2021-02-11 | — | — | US | disclosed |
| US-20210038535-A1 | PHARMACEUTICAL COMPOUND FOR TREATING COLORECTAL CANCER | LIAO SE CHUN (TW) | 2021-02-11 | — | — | US | disclosed |
| CN-112336704-A | Pharmaceutical composition for treating drug-resistant cancer | 永胜药品工业股份有限公司 | 2021-02-09 | — | — | CN | disclosed |
| WO-2021016987-A1 | PHARMACEUTICAL COMPOUND FOR TREATING COLORECTAL CANCER | EVEREST PHARM. INDUSTRIAL CO., LTD. (CN) | 2021-02-04 | — | — | WO | disclosed |
| CN-112305211-A | Method for controlling idiosyncratic hepatotoxicity of polygonum multiflorum | 北京圆融科技有限公司 | 2021-02-02 | — | — | CN | disclosed |
| US-10849861-B2 | Pharmaceutical compound for treating colorectal cancer | EVEREST PHARM. INDUSTRIAL CO., LTD. (TW) | 2020-12-01 | — | — | US | disclosed |
| US-10849861-B2 | Pharmaceutical compound for treating colorectal cancer | EVEREST PHARM. INDUSTRIAL CO., LTD. (TW) | 2020-12-01 | — | — | US | disclosed |
| US-20200038340-A1 | PHARMACEUTICAL COMPOUND FOR TREATING COLORECTAL CANCER | LIAO, SE-CHUN (TW) | 2020-02-06 | — | — | US | disclosed |
| US-20200038340-A1 | PHARMACEUTICAL COMPOUND FOR TREATING COLORECTAL CANCER | LIAO, SE-CHUN (TW) | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210038535-A1 | PHARMACEUTICAL COMPOUND FOR TREATING COLORECTAL CANCER | APC, CYP7A1, TCOF1 | PTPN1 1315/4885MAPT 2355/4885APP 3362/4885 |
| US-20200038340-A1 | PHARMACEUTICAL COMPOUND FOR TREATING COLORECTAL CANCER | APC, GPBAR1, CYP7A1 | PTPN1 1224/4885MAPT 2356/4885APP 3535/4885 |
| US-10849861-B2 | Pharmaceutical compound for treating colorectal cancer | APC, GPBAR1, CYP7A1 | PTPN1 1224/4885MAPT 2356/4885APP 3535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.