Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | CTSK | P43235 | 3/20 | 0.52 |
| ▸ | CTSL | P07711 | 2/20 | 0.52 |
| ▸ | CTSS | P25774 | 2/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5255204 | 0.86 | MAPT (0.62) | GAACTSKALDH1A1MAPTCA1 | |
| SCHEMBL6244636 | 0.82 | MAPT (0.58) | GAACTSKALDH1A1MAPTCA1 | |
| SCHEMBL21645364 | 0.78 | GAA (0.68) | GAAALDH1A1MAPTCA1CA2 | |
| SCHEMBL2453813 | 0.78 | GAA (0.73) | GAAALDH1A1MAPTCA1CA2 | |
| SCHEMBL28229111 | 0.73 | GAA (0.61) | GAAALDH1A1MAPTCA1CA2 | |
| SCHEMBL21645615 | 0.72 | GAA (0.60) | GAAALDH1A1MAPTCA1CA2 | |
| SCHEMBL23558026 | 0.68 | KCNH3 (0.53) | GAACTSKCTSLCTSSCTSB | |
| SCHEMBL10598128 | 0.68 | GAA (0.64) | GAAALDH1A1MAPTCA1CA2 | |
| SCHEMBL14869860 | 0.68 | ALDH1A1 (0.68) | GAAALDH1A1MAPTCA1CA2 | |
| SCHEMBL14388023 | 0.68 | ALDH1A1 (0.68) | GAAALDH1A1MAPTCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019241787-A9 | NOVEL CYCLIC GMP-AMP SYNTHASE (CGAS) INHIBITORS AND THEIR METHOD OF USE | THE REGENTS OF THE UNIVERSITY OF COLORADO A BODY CORPORATE (US) | 2020-02-06 | — | — | WO | disclosed |