Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA5A | P35218 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 2/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17544182 | 0.87 | GAA (0.39) | GAACA2STSCA1CA9 | |
| SCHEMBL15201850 | 0.85 | HSD11B1 (0.36) | CA2STSCA1CA9 | |
| SCHEMBL996026 | 0.79 | CA12 (0.41) | ALDH1A1KDM4EGAACA2CA5A | |
| SCHEMBL668901 | 0.79 | CA12 (0.41) | ALDH1A1KDM4EGAACA2CA5A | |
| Tetrabuthylammonium SCHEMBL26090987 | 0.77 | FUT7 (0.34) | ALDH1A1KDM4EGAATDP1L3MBTL1 | |
| SCHEMBL23199781 | 0.76 | STS (0.39) | CA2STSCA1 | |
| SCHEMBL9938274 | 0.76 | ELANE (0.38) | ALDH1A1CA2HPGDCA12CA9 | |
| SCHEMBL9938547 | 0.76 | KDM4E (0.40) | ALDH1A1KDM4EGAAHPGDSMN1; SMN2 | |
| SCHEMBL9938614 | 0.76 | MEN1 (0.42) | CA2 | |
| SCHEMBL9938199 | 0.76 | PDGFRB (0.41) | ALDH1A1KDM4EGAAL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3829589-A1 | METHODS OF ACTIVATING MICROGLIAL CELLS | The Research Foundation for the State University of New York (US) | 2021-06-09 | — | — | EP | disclosed |
| WO-2020028552-A1 | METHODS OF ACTIVATING MICROGLIAL CELLS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2020-02-06 | — | — | WO | disclosed |