Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23199823 | 0.99 | PDGFRB (0.40) | PDGFRBPDGFRAPRKCEMAOALMNA | |
| SCHEMBL23199818 | 0.89 | HTR1A (0.35) | PDGFRBPDGFRAPRKCEMAOALMNA | |
| SCHEMBL9938547 | 0.87 | KDM4E (0.40) | PDGFRBPDGFRAMAOALMNAL3MBTL1 | |
| SCHEMBL996026 | 0.83 | CA12 (0.41) | LMNAKDM4EALDH1A1GLAGAA | |
| SCHEMBL668901 | 0.83 | CA12 (0.41) | LMNAKDM4EALDH1A1GLAGAA | |
| SCHEMBL30645497 | 0.81 | KMT2A (0.42) | PDGFRBPDGFRAHTR1AHTR1BKDM4E | |
| SCHEMBL9938274 | 0.80 | ELANE (0.38) | LMNAL3MBTL1HTR1DHTR1BALDH1A1 | |
| SCHEMBL9938614 | 0.80 | MEN1 (0.42) | HTR1DHTR1BKMT2A | |
| SCHEMBL9938270 | 0.80 | ACHE (0.40) | — | |
| SCHEMBL19253296 | 0.79 | NCEH1 (0.30) | NCEH1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3801553-A2 | PRODRUGS OF FULVESTRANT | Kashiv Biosciences, LLC (US) | 2021-04-14 | — | — | EP | disclosed |
| EP-2651916-A2 | C-17-HETEROARYL STEROIDAL COMPOUNDS AS INHIBITORS OF CYP11B, CYP17, AND/OR CYP21 | BioMarin Pharmaceutical Inc. (US) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012083112-A2 | CYP11B, CYP17, AND/OR CYP21 INHIBITORS | BIOMARIN PHARMACEUTICAL INC. (US) | 2012-06-21 | — | — | WO | disclosed |