Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MLLT1 | Q03111 | 2/20 | 0.32 |
| ▸ | MLLT3 | P42568 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25124546 | 0.82 | MAPK1 (0.39) | MAPK1ALOX5APFEN1CYP2C9MLLT1 | |
| SCHEMBL25124548 | 0.77 | CYP2C9 (0.37) | MAPK1ALOX5APFEN1CYP2C9MLLT1 | |
| SCHEMBL23055261 | 0.77 | MAPK1 (0.36) | MAPK1ALOX5APFEN1CYP2C9MLLT1 | |
| SCHEMBL22124957 | 0.72 | MLLT1 (0.45) | MAPK1ALOX5APFEN1CYP2C9MLLT1 | |
| SCHEMBL12093722 | 0.71 | SMN1; SMN2 (0.43) | MAPK1ALOX5APFEN1CYP2C9 | |
| SCHEMBL21646360 | 0.70 | PRKCI (0.39) | — | |
| SCHEMBL23817244 | 0.67 | ALDH1A1 (0.45) | MAPK1CYP2C9 | |
| SCHEMBL21580045 | 0.67 | TLR9 (0.46) | MAPK1ALOX5APFEN1CYP2C9 | |
| SCHEMBL15907160 | 0.67 | MLLT1 (0.40) | MAPK1ALOX5APFEN1CYP2C9MLLT1 | |
| Hydrochloric Acid SCHEMBL22124411 | 0.66 | TLR9 (0.36) | MAPK1ALOX5APFEN1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020017587-A1 | PYRIDAZINONE DERIVATIVE | 大日本住友製薬株式会社 | 2020-01-23 | — | — | WO | disclosed |