Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23055267 | 0.77 | PRKCI (0.39) | PRKCITBXAS1BRD4CREBBPNR3C1 | |
| SCHEMBL25124500 | 0.77 | TBXAS1 (0.40) | PRKCITBXAS1BRD4CREBBPNR3C1 | |
| SCHEMBL21646352 | 0.70 | MAPK1 (0.36) | — | |
| SCHEMBL23697851 | 0.70 | ESR1 (0.31) | — | |
| SCHEMBL24629446 | 0.69 | TBXAS1 (0.43) | PRKCITBXAS1NR3C1NAMPTNTRK1 | |
| SCHEMBL15246478 | 0.67 | TBXAS1 (0.43) | PRKCITBXAS1BRD4CREBBPNR3C1 | |
| SCHEMBL17561679 | 0.67 | TBXAS1 (0.40) | PRKCITBXAS1BRD4CREBBPNR3C1 | |
| SCHEMBL13931946 | 0.67 | QPCT (0.43) | PRKCITBXAS1BRD4CREBBP | |
| SCHEMBL15435640 | 0.67 | TBXAS1 (0.54) | PRKCITBXAS1BRD4CREBBPNR3C1 | |
| SCHEMBL31646996 | 0.65 | LMNA (0.39) | PRKCITBXAS1NAMPTNTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020017587-A1 | PYRIDAZINONE DERIVATIVE | 大日本住友製薬株式会社 | 2020-01-23 | — | — | WO | disclosed |